eF-site ID 2okj-A PDB Code 2okj Chain A click to enlarge Title The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67) Classification LYASE Compound Glutamate decarboxylase 1 Source null (DCE1_HUMAN) Sequence A:  TDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTF DRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDC RDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTN MFTYEIAPVFVLMEQITLKKMREIVGWSSKDGDGIFSPGG AISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEQSHY SIKKAGAALGFGTDNVILIKCNERGKIIPADFEAKILEAK QKGYVPFYVNATAGTTVYGAFDPIQEIADICEKYNLWLHV DAAWGGGLLMSRKHRHKLNGIERANSVTWNPHXMMGVLLQ CSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKA IQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYA KIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPQRR EKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISN PAATQSDIDFLIEEIERLGQD Description Functional site 1) chain A residue 190 type sequence Q description BINDING SITE FOR RESIDUE ABU A 1001 source : AC1 2) chain A residue 191 type sequence L description BINDING SITE FOR RESIDUE ABU A 1001 source : AC1 3) chain A residue 192 type sequence S description BINDING SITE FOR RESIDUE ABU A 1001 source : AC1 4) chain A residue 567 type sequence R description BINDING SITE FOR RESIDUE ABU A 1001 source : AC1 5) chain A residue 435 type sequence L description BINDING SITE FOR RESIDUE ABU B 1002 source : AC2 6) chain A residue 214 type sequence F description BINDING SITE FOR RESIDUE PLZ B 2001 source : AC3 7) chain A residue 455 type sequence C description BINDING SITE FOR RESIDUE PLZ B 2001 source : AC3 8) chain A residue 456 type sequence G description BINDING SITE FOR RESIDUE PLZ B 2001 source : AC3 9) chain A residue 398-419 type prosite sequence SVTWNPHXMMGVLLQCSAILVK description DDC_GAD_HDC_YDC DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. SVtWnphKMMgVlLQCsaILvK source prosite : PS00392 10) chain A residue 190 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:17384644, ECO:0007744|PDB:2OKJ source Swiss-Prot : SWS_FT_FI1 11) chain A residue 567 type BINDING sequence R description BINDING => ECO:0000269|PubMed:17384644, ECO:0007744|PDB:2OKJ source Swiss-Prot : SWS_FT_FI1 12) chain A residue 405 type MOD_RES sequence X description N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:17384644, ECO:0007744|PDB:2OKJ source Swiss-Prot : SWS_FT_FI2

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