eF-site ID 2ojr-A
PDB Code 2ojr
Chain A

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Title Structure of ubiquitin solved by SAD using the Lanthanide-Binding Tag
Classification PROTEIN BINDING
Compound Ubiquitin
Source (UBIQ_HUMAN)
Sequence A:  GPGYIDTNNDGWIEGDELYIDTNNDGWIEGDELLAMQIFV
KTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIF
AGKQLEDGRTLSDYNIQKESTLHLVLRLRG
Description


Functional site

1) chain A
residue 71
type
sequence D
description BINDING SITE FOR RESIDUE TB A 500
source : AC1

2) chain A
residue 73
type
sequence N
description BINDING SITE FOR RESIDUE TB A 500
source : AC1

3) chain A
residue 75
type
sequence D
description BINDING SITE FOR RESIDUE TB A 500
source : AC1

4) chain A
residue 77
type
sequence W
description BINDING SITE FOR RESIDUE TB A 500
source : AC1

5) chain A
residue 79
type
sequence E
description BINDING SITE FOR RESIDUE TB A 500
source : AC1

6) chain A
residue 82
type
sequence E
description BINDING SITE FOR RESIDUE TB A 500
source : AC1

7) chain A
residue 86
type
sequence D
description BINDING SITE FOR RESIDUE TB A 501
source : AC2

8) chain A
residue 88
type
sequence N
description BINDING SITE FOR RESIDUE TB A 501
source : AC2

9) chain A
residue 90
type
sequence D
description BINDING SITE FOR RESIDUE TB A 501
source : AC2

10) chain A
residue 92
type
sequence W
description BINDING SITE FOR RESIDUE TB A 501
source : AC2

11) chain A
residue 94
type
sequence E
description BINDING SITE FOR RESIDUE TB A 501
source : AC2

12) chain A
residue 97
type
sequence E
description BINDING SITE FOR RESIDUE TB A 501
source : AC2

13) chain A
residue 111
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144
source Swiss-Prot : SWS_FT_FI8

14) chain A
residue 148
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144
source Swiss-Prot : SWS_FT_FI8

15) chain A
residue 154
type SITE
sequence R
description Interacts with activating enzyme
source Swiss-Prot : SWS_FT_FI1

16) chain A
residue 172
type SITE
sequence R
description Interacts with activating enzyme
source Swiss-Prot : SWS_FT_FI1

17) chain A
residue 168
type SITE
sequence H
description Essential for function
source Swiss-Prot : SWS_FT_FI2

18) chain A
residue 165
type MOD_RES
sequence S
description Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291
source Swiss-Prot : SWS_FT_FI3

19) chain A
residue 166
type MOD_RES
sequence T
description (Microbial infection) ADP-ribosylthreonine => ECO:0000269|PubMed:32330457
source Swiss-Prot : SWS_FT_FI4

20) chain A
residue 163
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106
source Swiss-Prot : SWS_FT_FI12

21) chain A
residue 106
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603
source Swiss-Prot : SWS_FT_FI6

22) chain A
residue 127
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860
source Swiss-Prot : SWS_FT_FI9

23) chain A
residue 129
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127
source Swiss-Prot : SWS_FT_FI10

24) chain A
residue 133
type CROSSLNK
sequence K
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577
source Swiss-Prot : SWS_FT_FI11

25) chain A
residue 71-83
type prosite
sequence DTNNDGWIEGDEL
description EF_HAND_1 EF-hand calcium-binding domain. DTNNDGWIEgdEL
source prosite : PS00018

26) chain A
residue 86-98
type prosite
sequence DTNNDGWIEGDEL
description EF_HAND_1 EF-hand calcium-binding domain. DTNNDGWIEgdEL
source prosite : PS00018

27) chain A
residue 127-152
type prosite
sequence KAKIQDKEGIPPDQQRLIFAGKQLED
description UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD
source prosite : PS00299


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