|
eF-site ID
|
2oje-A |
PDB Code
|
2oje |
Chain
|
A |
|
click to enlarge
|
|
Title
|
Mycoplasma arthritidis-derived mitogen complexed with class II MHC molecule HLA-DR1/HA complex in the presence of EDTA |
Classification
|
IMMUNE SYSTEM |
Compound
|
HLA class II histocompatibility antigen, DR alpha chain precursor |
Source
|
Homo sapiens (Human) (2OJE) |
|
Sequence
|
A: |
KEEHVIIQAEFYLNPDQSGEFXFDFDGDEIFHVDXAKKET
VWRLEEFGRFASFEAQGALANIAVDKANLEIXTKRSNYTP
ITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTW
LRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVY
DCRVEHWGLDEPLLKHWEFD
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
61 |
type |
|
sequence |
A
|
description |
BINDING SITE FOR RESIDUE PO4 D 214
|
source |
: AC1
|
|
2)
|
chain |
A |
residue |
58 |
type |
|
sequence |
G
|
description |
BINDING SITE FOR RESIDUE PO4 C 202
|
source |
: AC2
|
|
3)
|
chain |
A |
residue |
161-167 |
type |
prosite |
sequence |
YDCRVEH
|
description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCRVEH
|
source |
prosite : PS00290
|
|
4)
|
chain |
A |
residue |
53 |
type |
SITE |
sequence |
S
|
description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819
|
source |
Swiss-Prot : SWS_FT_FI4
|
|
5)
|
chain |
A |
residue |
55 |
type |
SITE |
sequence |
E
|
description |
Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX
|
source |
Swiss-Prot : SWS_FT_FI5
|
|
6)
|
chain |
A |
residue |
62 |
type |
SITE |
sequence |
N
|
description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX
|
source |
Swiss-Prot : SWS_FT_FI6
|
|
7)
|
chain |
A |
residue |
69 |
type |
SITE |
sequence |
N
|
description |
Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
|
source |
Swiss-Prot : SWS_FT_FI7
|
|
8)
|
chain |
A |
residue |
76 |
type |
SITE |
sequence |
R
|
description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
|
source |
Swiss-Prot : SWS_FT_FI8
|
|
9)
|
chain |
A |
residue |
78 |
type |
CARBOHYD |
sequence |
N
|
description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
|
source |
Swiss-Prot : SWS_FT_FI9
|
|
10)
|
chain |
A |
residue |
118 |
type |
CARBOHYD |
sequence |
N
|
description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
|
source |
Swiss-Prot : SWS_FT_FI9
|
|
|
|