eF-site ID 2oje-A
PDB Code 2oje
Chain A

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Title Mycoplasma arthritidis-derived mitogen complexed with class II MHC molecule HLA-DR1/HA complex in the presence of EDTA
Classification IMMUNE SYSTEM
Compound HLA class II histocompatibility antigen, DR alpha chain precursor
Source Homo sapiens (Human) (2OJE)
Sequence A:  KEEHVIIQAEFYLNPDQSGEFXFDFDGDEIFHVDXAKKET
VWRLEEFGRFASFEAQGALANIAVDKANLEIXTKRSNYTP
ITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTW
LRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVY
DCRVEHWGLDEPLLKHWEFD
Description


Functional site

1) chain A
residue 61
type
sequence A
description BINDING SITE FOR RESIDUE PO4 D 214
source : AC1

2) chain A
residue 58
type
sequence G
description BINDING SITE FOR RESIDUE PO4 C 202
source : AC2

3) chain A
residue 161-167
type prosite
sequence YDCRVEH
description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCRVEH
source prosite : PS00290

4) chain A
residue 53
type SITE
sequence S
description Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819
source Swiss-Prot : SWS_FT_FI4

5) chain A
residue 55
type SITE
sequence E
description Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX
source Swiss-Prot : SWS_FT_FI5

6) chain A
residue 62
type SITE
sequence N
description Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX
source Swiss-Prot : SWS_FT_FI6

7) chain A
residue 69
type SITE
sequence N
description Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
source Swiss-Prot : SWS_FT_FI7

8) chain A
residue 76
type SITE
sequence R
description Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
source Swiss-Prot : SWS_FT_FI8

9) chain A
residue 78
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
source Swiss-Prot : SWS_FT_FI9

10) chain A
residue 118
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
source Swiss-Prot : SWS_FT_FI9


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