eF-site ID 2oat-A PDB Code 2oat Chain A click to enlarge Title ORNITHINE AMINOTRANSFERASE COMPLEXED WITH 5-FLUOROMETHYLORNITHINE Classification AMINOTRANSFERASE Compound ORNITHINE AMINOTRANSFERASE Source Homo sapiens (Human) (OAT_HUMAN) Sequence A:  GPPTSDDIFEREYKYGAHNYHPLPVALERGKGIYLWDVEG RKYFDFLSSYSAVNQGHCHPKIVNALKSQVDKLTLTSRAF YNNVLGEYEEYITKLFNYHKVLPMNTGVEAGETACKLARK WGYTVKGIQKYKAKIVFAAGNFWGRTLSAISSSTDPTSYD GFGPFMPGFDIIPYNDLPALERALQDPNVAAFMVEPIQGE AGVVVPDPGYLMGVRELCTRHQVLFIADEIQTGLARTGRW LAVDYENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIK PGEHGSTYGGNPLGCRVAIAALEVLEEENLAENADKLGII LRNELMKLPSDVVTAVRGKGLLNAIVIKETKDWDAWKVCL RLRDNGLLAKPTHGDIIRFAPPLVIKEDELRESIEIINKT ILSF Description Functional site 1) chain A residue 55 type sequence Y description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 2) chain A residue 141 type sequence T description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 3) chain A residue 142 type sequence G description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 4) chain A residue 143 type sequence V description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 5) chain A residue 177 type sequence F description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 6) chain A residue 178 type sequence W description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 7) chain A residue 180 type sequence R description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 8) chain A residue 230 type sequence E description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 9) chain A residue 235 type sequence E description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 10) chain A residue 263 type sequence D description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 11) chain A residue 266 type sequence Q description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 12) chain A residue 292 type sequence K description BINDING SITE FOR RESIDUE PFM A 440 source : AC1 13) chain A residue 320 type sequence G description BINDING SITE FOR RESIDUE PFM B 440 source : AC2 14) chain A residue 321 type sequence S description BINDING SITE FOR RESIDUE PFM B 440 source : AC2 15) chain A residue 322 type sequence T description BINDING SITE FOR RESIDUE PFM B 440 source : AC2 16) chain A residue 177 type catalytic sequence F description 929 source MCSA : MCSA1 17) chain A residue 263 type catalytic sequence D description 929 source MCSA : MCSA1 18) chain A residue 292 type catalytic sequence K description 929 source MCSA : MCSA1 19) chain A residue 260-297 type prosite sequence FIADEIQTGLARTGRWLAVDYENVRPDIVLLGKALSGG description AA_TRANSFER_CLASS_3 Aminotransferases class-III pyridoxal-phosphate attachment site. FIaDEIqt.GLaRtGrwlavdyenvrp....DIVllGKalsGG source prosite : PS00600 20) chain A residue 49 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P29758 source Swiss-Prot : SWS_FT_FI1 21) chain A residue 66 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P29758 source Swiss-Prot : SWS_FT_FI1 22) chain A residue 386 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P29758 source Swiss-Prot : SWS_FT_FI1 23) chain A residue 392 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P29758 source Swiss-Prot : SWS_FT_FI1 24) chain A residue 421 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P29758 source Swiss-Prot : SWS_FT_FI1 25) chain A residue 102 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:P29758 source Swiss-Prot : SWS_FT_FI2 26) chain A residue 107 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P29758 source Swiss-Prot : SWS_FT_FI3 27) chain A residue 362 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P29758 source Swiss-Prot : SWS_FT_FI3 28) chain A residue 405 type MOD_RES sequence K description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P29758 source Swiss-Prot : SWS_FT_FI3 29) chain A residue 292 type MOD_RES sequence K description N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:3754226 source Swiss-Prot : SWS_FT_FI4

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