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|
eF-site ID
|
2o7m-B |
|
PDB Code
|
2o7m |
|
Chain
|
B |
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click to enlarge
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Title
|
The C-terminal loop of the homing endonuclease I-CreI is essential for DNA binding and cleavage. Identification of a novel site for specificity engineering in the I-CreI scaffold |
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Classification
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HYDROLASE |
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Compound
|
DNA endonuclease I-CreI |
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Source
|
Chlamydomonas reinhardtii (Chlamydomonas smithii) (DNE1_CHLRE) |
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|
Sequence
|
B: |
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSL
TFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSDYILSEI
KPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDK
FLEVCTWVDQIAALNDSKTRKTTSETVRAVLDS
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Description
|
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Functional site
|
|
|
1)
|
chain |
B |
| residue |
19 |
| type |
catalytic |
| sequence |
G
|
| description |
233
|
| source |
MCSA : MCSA2
|
|
|
2)
|
chain |
B |
| residue |
20 |
| type |
catalytic |
| sequence |
D
|
| description |
233
|
| source |
MCSA : MCSA2
|
|
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3)
|
chain |
B |
| residue |
19 |
| type |
BINDING |
| sequence |
G
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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4)
|
chain |
B |
| residue |
20 |
| type |
BINDING |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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|