|
|
eF-site ID
|
2o3t-B |
|
PDB Code
|
2o3t |
|
Chain
|
B |
|
click to enlarge
|
|
|
Title
|
Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by Human CD38 |
|
Classification
|
HYDROLASE |
|
Compound
|
ADP-ribosyl cyclase 1 |
|
Source
|
Homo sapiens (Human) (CD38_HUMAN) |
|
|
Sequence
|
B: |
RWRQTWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQS
VWDAFKGAFISKHPCDITEEDYQPLMKLGTQTVPCNKILL
WSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFD
TSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVV
HVMLDGSRSKIFDKDSTFGSVQVHNLQPEKVQTLEAWVIH
GGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKF
LQCVKNPEDSSC
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
100 |
| type |
CARBOHYD |
| sequence |
D
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
B |
| residue |
209 |
| type |
CARBOHYD |
| sequence |
D
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
B |
| residue |
164 |
| type |
CARBOHYD |
| sequence |
D
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
B |
| residue |
219 |
| type |
CARBOHYD |
| sequence |
D
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
5)
|
chain |
B |
| residue |
119 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
ACT_SITE => ECO:0000305|PubMed:7961800
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
B |
| residue |
201 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
ACT_SITE => ECO:0000305|PubMed:7961800
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|