eF-site ID 2o3r-B PDB Code 2o3r Chain B click to enlarge Title Structural Basis for Formation and Hydrolysis of Calcium Messenger Cyclic ADP-ribose by Human CD38 Classification HYDROLASE Compound ADP-ribosyl cyclase 1 Source Homo sapiens (Human) (CD38_HUMAN) Sequence B:  RWRQTWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQS VWDAFKGAFISKHPCDITEEDYQPLMKLGTQTVPCNKILL WSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFD TSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVV HVMLDGSRSKIFDKDSTFGSVDVHNLQPEKVQTLEAWVIH GGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKF LQCVKNPEDSSC Description Functional site 1) chain B residue 125 type sequence W description BINDING SITE FOR RESIDUE CXR B 301 source : AC2 2) chain B residue 129 type sequence K description BINDING SITE FOR RESIDUE CXR B 301 source : AC2 3) chain B residue 146 type sequence E description BINDING SITE FOR RESIDUE CXR B 301 source : AC2 4) chain B residue 155 type sequence D description BINDING SITE FOR RESIDUE CXR B 301 source : AC2 5) chain B residue 156 type sequence D description BINDING SITE FOR RESIDUE CXR B 301 source : AC2 6) chain B residue 185 type sequence V description BINDING SITE FOR RESIDUE CXR B 301 source : AC2 7) chain B residue 189 type sequence W description BINDING SITE FOR RESIDUE CXR B 301 source : AC2 8) chain B residue 221 type sequence T description BINDING SITE FOR RESIDUE CXR B 301 source : AC2 9) chain B residue 164 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 10) chain B residue 219 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973 source Swiss-Prot : SWS_FT_FI4 11) chain B residue 119 type ACT_SITE sequence C description ACT_SITE => ECO:0000305|PubMed:7961800 source Swiss-Prot : SWS_FT_FI1 12) chain B residue 201 type ACT_SITE sequence C description ACT_SITE => ECO:0000305|PubMed:7961800 source Swiss-Prot : SWS_FT_FI1 13) chain B residue 100 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 source Swiss-Prot : SWS_FT_FI2 14) chain B residue 209 type CARBOHYD sequence D description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 source Swiss-Prot : SWS_FT_FI2

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