eF-site ID 2npp-F PDB Code 2npp Chain F click to enlarge Title Structure of the Protein Phosphatase 2A Holoenzyme Classification HYDROLASE/HYDROLASE INHIBITOR Compound Protein Phosphatase 2, regulatory subunit A (PR 65), alpha isoform Source null (NOR00109) Sequence F:  DEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTK ESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYL FMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESR QITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDG QIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWS DPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAH QLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDT LKYSFLQFDPAPRRGEPHVTRRTPDYFL Description Functional site 1) chain F residue 85 type sequence D description BINDING SITE FOR RESIDUE MN F 501 source : AC3 2) chain F residue 117 type sequence N description BINDING SITE FOR RESIDUE MN F 501 source : AC3 3) chain F residue 167 type sequence H description BINDING SITE FOR RESIDUE MN F 501 source : AC3 4) chain F residue 241 type sequence H description BINDING SITE FOR RESIDUE MN F 501 source : AC3 5) chain F residue 57 type sequence D description BINDING SITE FOR RESIDUE MN F 502 source : AC4 6) chain F residue 59 type sequence H description BINDING SITE FOR RESIDUE MN F 502 source : AC4 7) chain F residue 85 type sequence D description BINDING SITE FOR RESIDUE MN F 502 source : AC4 8) chain F residue 117 type BINDING sequence N description BINDING => ECO:0000269|PubMed:17055435 source Swiss-Prot : SWS_FT_FI2 9) chain F residue 167 type BINDING sequence H description BINDING => ECO:0000269|PubMed:17055435 source Swiss-Prot : SWS_FT_FI2 10) chain F residue 241 type BINDING sequence H description BINDING => ECO:0000269|PubMed:17055435 source Swiss-Prot : SWS_FT_FI2 11) chain F residue 57 type BINDING sequence D description BINDING => ECO:0000269|PubMed:17055435 source Swiss-Prot : SWS_FT_FI2 12) chain F residue 59 type BINDING sequence H description BINDING => ECO:0000269|PubMed:17055435 source Swiss-Prot : SWS_FT_FI2 13) chain F residue 85 type BINDING sequence D description BINDING => ECO:0000269|PubMed:17055435 source Swiss-Prot : SWS_FT_FI2 14) chain F residue 307 type MOD_RES sequence Y description Phosphotyrosine => ECO:0000250|UniProtKB:P67774 source Swiss-Prot : SWS_FT_FI3 15) chain F residue 309 type MOD_RES sequence L description Leucine methyl ester => ECO:0000269|PubMed:8206937 source Swiss-Prot : SWS_FT_FI4

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