|
|
eF-site ID
|
2nlu_8-AB |
|
PDB Code
|
2nlu |
|
Model
|
8 |
|
Chain
|
A, B |
|
click to enlarge
|
|
|
Title
|
Domain-Swapped Dimer of the PWWP Module of Human Hepatoma-derived Growth Factor |
|
Classification
|
HORMONE/GROWTH FACTOR |
|
Compound
|
Hepatoma-derived growth factor |
|
Source
|
null (HDGF_HUMAN) |
|
|
Sequence
|
A: |
MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKS
TANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRK
GFSEGLWEIENNPTVKASGY
|
| B: |
MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKS
TANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRK
GFSEGLWEIENNPTVKASGY
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
119 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
121 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
172 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
B |
| residue |
175 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
B |
| residue |
179 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
B |
| residue |
180 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
A |
| residue |
19 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
A |
| residue |
21 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
A |
| residue |
72 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
A |
| residue |
75 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
11)
|
chain |
A |
| residue |
79 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
12)
|
chain |
A |
| residue |
80 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
13)
|
chain |
A |
| residue |
44 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
14)
|
chain |
B |
| residue |
144 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
15)
|
chain |
B |
| residue |
180 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
16)
|
chain |
A |
| residue |
80 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|