eF-site ID 2nll-A
PDB Code 2nll
Chain A

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Title RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA
Classification TRANSCRIPTION/DNA
Compound DNA (5'-D(*CP*AP*GP*GP*TP*CP*AP*TP*TP*(5IU)P*CP*AP*GP*GP*TP*CP*AP*G)-3')
Source null (2NLL)
Sequence A:  CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDN
KDCLIDKRQRNRCQYCRYQKCLAMGM
Description


Functional site

1) chain A
residue 135
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 250
source : AC1

2) chain A
residue 138
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 250
source : AC1

3) chain A
residue 152
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 250
source : AC1

4) chain A
residue 155
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 250
source : AC1

5) chain A
residue 171
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 251
source : AC2

6) chain A
residue 177
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 251
source : AC2

7) chain A
residue 187
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 251
source : AC2

8) chain A
residue 190
type
sequence C
description BINDING SITE FOR RESIDUE ZN A 251
source : AC2

9) chain A
residue 135-161
type prosite
sequence CAICGDRSSGKHYGVYSCEGCKGFFKR
description NUCLEAR_REC_DBD_1 Nuclear hormones receptors DNA-binding region signature. CaiCg.Drssgk.HYgvysCegCkgFFkR
source prosite : PS00031

10) chain A
residue 145
type MOD_RES
sequence K
description N6-acetyllysine; by EP300 => ECO:0000269|PubMed:17761950
source Swiss-Prot : SWS_FT_FI4


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