eF-site ID 2mmt_13-A PDB Code 2mmt Model 13 Chain A click to enlarge Title Lasso peptide-based integrin inhibitor: Microcin J25 variant with RGDF substitution of Gly12-Ile13-Gly14-Thr15 Classification ANTIBIOTIC Compound Microcin J25 RGDF mutant Source Escherichia coli (MCJA_ECOLX) Sequence A:  GGAGHVPEYFVRGDFPISFYG Description (1)  Microcin J25 Functional site 1) chain A residue 4 type SITE sequence G description Essential for permeation into bacteria => ECO:0000269|PubMed:18632663 source Swiss-Prot : SWS_FT_FI1 2) chain A residue 7 type SITE sequence P description Essential for permeation into bacteria => ECO:0000269|PubMed:18632663 source Swiss-Prot : SWS_FT_FI1 3) chain A residue 10 type SITE sequence F description Essential for permeation into bacteria => ECO:0000269|PubMed:18632663 source Swiss-Prot : SWS_FT_FI1 4) chain A residue 19 type SITE sequence F description Essential for permeation into bacteria => ECO:0000269|PubMed:18632663 source Swiss-Prot : SWS_FT_FI1 5) chain A residue 20 type SITE sequence Y description Essential for permeation into bacteria => ECO:0000269|PubMed:18632663 source Swiss-Prot : SWS_FT_FI1 6) chain A residue 9 type SITE sequence Y description Essential for permeation into bacteria and for RNAP inhibition => ECO:0000269|PubMed:18632663 source Swiss-Prot : SWS_FT_FI2 7) chain A residue 8 type CROSSLNK sequence E description Isoglutamyl glycine isopeptide (Gly-Glu) => ECO:0000269|PubMed:14531661, ECO:0000269|PubMed:14531690, ECO:0000269|PubMed:14531691 source Swiss-Prot : SWS_FT_FI3 8) chain A residue 1 type CROSSLNK sequence G description Isoglutamyl glycine isopeptide (Gly-Glu) => ECO:0000269|PubMed:14531661, ECO:0000269|PubMed:14531690, ECO:0000269|PubMed:14531691 source Swiss-Prot : SWS_FT_FI3

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