|
eF-site ID
|
2mej_10-A |
PDB Code
|
2mej |
Model
|
10 |
Chain
|
A |
|
click to enlarge
|
|
Title
|
Solution Structure of the Complex Between BCL-xL and the p53 Core Domain determined with PRE restraints |
Classification
|
APOPTOSIS |
Compound
|
Bcl-2-like protein 1 |
Source
|
Homo sapiens (Human) (P53_HUMAN) |
|
Sequence
|
A: |
MSQSNRELVVDFLSYKLSQKGYSWSQFSMAAVKQALREAG
DEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG
VNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYL
NDHLEPWIQENGGWDTFVELYGNN
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
133-151 |
type |
prosite |
sequence |
LFRDGVNWGRIVAFFSFGG
|
description |
BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG
|
source |
prosite : PS01080
|
|
2)
|
chain |
A |
residue |
184-195 |
type |
prosite |
sequence |
WIQENGGWDTFV
|
description |
BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV
|
source |
prosite : PS01258
|
|
3)
|
chain |
A |
residue |
89-103 |
type |
prosite |
sequence |
VKQALREAGDEFELR
|
description |
BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR
|
source |
prosite : PS01259
|
|
4)
|
chain |
A |
residue |
7-27 |
type |
prosite |
sequence |
SNRELVVDFLSYKLSQKGYSW
|
description |
BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW
|
source |
prosite : PS01260
|
|
|
|