eF-site ID 2lxp_6-ABC PDB Code 2lxp Model 6 Chain A, B, C click to enlarge Title NMR structure of two domains in ubiquitin ligase gp78, RING and G2BR, bound to its conjugating enzyme Ube2g Classification LIGASE Compound Ubiquitin-conjugating enzyme E2 G2 Source null (AMFR2_HUMAN) Sequence A:  AGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALI MGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPN IYPDGRVCISILHAPGSAERWSPVQSVEKILLSVVSMLAE PNDESGANVDASKMWRDDREQFYKIAKQIVQKSLGL B:  SADERQRMLVQRKDELLQQARKRFLNK C:  AVATPEELAVNNDDCAICWDSMQAARKLPCGHLFHNSCLR SWLEQDTSCPTCRMSLNI Description Functional site 1) chain C residue 341 type sequence C description BINDING SITE FOR RESIDUE ZN C 900 source : AC1 2) chain C residue 344 type sequence C description BINDING SITE FOR RESIDUE ZN C 900 source : AC1 3) chain C residue 361 type sequence H description BINDING SITE FOR RESIDUE ZN C 900 source : AC1 4) chain C residue 364 type sequence C description BINDING SITE FOR RESIDUE ZN C 900 source : AC1 5) chain C residue 356 type sequence C description BINDING SITE FOR RESIDUE ZN C 901 source : AC2 6) chain C residue 358 type sequence H description BINDING SITE FOR RESIDUE ZN C 901 source : AC2 7) chain C residue 375 type sequence C description BINDING SITE FOR RESIDUE ZN C 901 source : AC2 8) chain C residue 378 type sequence C description BINDING SITE FOR RESIDUE ZN C 901 source : AC2 9) chain C residue 341-379 type ZN_FING sequence CAICWDSMQAARKLPCGHLFHNSCLRSWLEQDTSCPTCR description RING-type => ECO:0000255|PROSITE-ProRule:PRU00175 source Swiss-Prot : SWS_FT_FI1 10) chain A residue 2 type MOD_RES sequence A description N-acetylalanine => ECO:0007744|PubMed:25944712 source Swiss-Prot : SWS_FT_FI2 11) chain A residue 78-93 type prosite sequence FHPNIYPDGRVCISIL description UBC_1 Ubiquitin-conjugating (UBC) active site signature. FHPNIypd.GrVCIsiL source prosite : PS00183

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