eF-site ID 2lnl_9-A PDB Code 2lnl Model 9 Chain A click to enlarge Title Structure of human CXCR1 in phospholipid bilayers Classification SIGNALING PROTEIN Compound C-X-C chemokine receptor type 1 Source null (CXCR1_HUMAN) Sequence A:  PCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSR VGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTF LCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQ KRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHPNNSSPVCY EVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRT LFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLM RTQVIQESCERRNNIGRALDATEILGFLHSCLNPIIYAFI GQNFRHGFLKILAMHG Description (1)  C-X-C chemokine receptor type 1 Functional site 1) chain A residue 40-66 type TRANSMEM sequence YVVIIAYALVFLLSLLGNSLVMLVILY description Helical; Name=1 => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 2) chain A residue 67-75 type TOPO_DOM sequence SRVGRSVTD description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 3) chain A residue 134-154 type TOPO_DOM sequence DRYLAIVHATRTLTQKRHLVK description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 4) chain A residue 221-242 type TOPO_DOM sequence CYGFTLRTLFKAHMGQKHRAMR description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 5) chain A residue 76-96 type TRANSMEM sequence VYLLNLALADLLFALTLPIWA description Helical; Name=2 => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 6) chain A residue 97-111 type TOPO_DOM sequence ASKVNGWIFGTFLCK description Extracellular => ECO:0000255 source Swiss-Prot : SWS_FT_FI4 7) chain A residue 175-199 type TOPO_DOM sequence RQAYHPNNSSPVCYEVLGNDTAKWR description Extracellular => ECO:0000255 source Swiss-Prot : SWS_FT_FI4 8) chain A residue 265-285 type TOPO_DOM sequence DTLMRTQVIQESCERRNNIGR description Extracellular => ECO:0000255 source Swiss-Prot : SWS_FT_FI4 9) chain A residue 112-133 type TRANSMEM sequence VVSLLKEVNFYSGILLLACISV description Helical; Name=3 => ECO:0000255 source Swiss-Prot : SWS_FT_FI5 10) chain A residue 155-174 type TRANSMEM sequence FVCLGCWGLSMNLSLPFFLF description Helical; Name=4 => ECO:0000255 source Swiss-Prot : SWS_FT_FI6 11) chain A residue 200-220 type TRANSMEM sequence MVLRILPHTFGFIVPLFVMLF description Helical; Name=5 => ECO:0000255 source Swiss-Prot : SWS_FT_FI7 12) chain A residue 243-264 type TRANSMEM sequence VIFAVVLIFLLCWLPYNLVLLA description Helical; Name=6 => ECO:0000255 source Swiss-Prot : SWS_FT_FI8 13) chain A residue 286-308 type TRANSMEM sequence ALDATEILGFLHSCLNPIIYAFI description Helical; Name=7 => ECO:0000255 source Swiss-Prot : SWS_FT_FI9 14) chain A residue 123-139 type prosite sequence SGILLLACISVDRYLAI description G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. SGIlLLACISVDRYLaI source prosite : PS00237

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