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|
eF-site ID
|
2leh_2-AB |
|
PDB Code
|
2leh |
|
Model
|
2 |
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Chain
|
A, B |
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click to enlarge
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Title
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Solution structure of the core SMN-Gemin2 complex |
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Classification
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PROTEIN BINDING |
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Compound
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Survival of motor neuron protein-interacting protein 1 |
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Source
|
Homo sapiens (Human) (SMN_HUMAN) |
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Sequence
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A: |
GYSPTLQWQQQQVAQFSTVRQNVNKHRSHWKSQQLDSNVT
MPKSEDEEGWKKFCLGEKLCADGAVGPATNESPGIDYVQI
GFPPLLSIVSRMNQATVTSVLEYLSNWFGERDFTPELGRW
LYALLACLEKPLLPEAHSLIRQLARRCSEVRLLVDSKDDE
RVPALNLLICLVSRYFDQRDLADEPSLEY
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| B: |
GQSDDSDIWDDTALIKAYDKAVASFK
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Description
|
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Functional site
|
|
|
1)
|
chain |
B |
| residue |
31 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:17487921, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19369195, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
|
| source |
Swiss-Prot : SWS_FT_FI2
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|
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2)
|
chain |
B |
| residue |
28 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19369195, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
51 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
|
| source |
Swiss-Prot : SWS_FT_FI3
|
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