|
eF-site ID
|
2lbm_21-C |
PDB Code
|
2lbm |
Model
|
21 |
Chain
|
C |
|
click to enlarge
|
|
Title
|
Solution structure of the ADD domain of ATRX complexed with histone tail H3 1-15 K9me3 |
Classification
|
METAL BINDING PROTEIN/STRUCTURAL PROTEIN |
Compound
|
Transcriptional regulator ATRX |
Source
|
Homo sapiens (Human) (2LBM) |
|
Sequence
|
C: |
ARTKQTARXSTGGKA
|
|
Description
|
(1) |
Transcriptional regulator ATRX (E.C.3.6.4.12), histone tail H3 K9me3
|
|
Functional site
|
|
1)
|
chain |
C |
residue |
2 |
type |
MOD_RES |
sequence |
R
|
description |
Citrulline; alternate => ECO:0000269|PubMed:16567635
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
2)
|
chain |
C |
residue |
14 |
type |
MOD_RES |
sequence |
K
|
description |
N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435
|
source |
Swiss-Prot : SWS_FT_FI10
|
|
3)
|
chain |
C |
residue |
3 |
type |
MOD_RES |
sequence |
T
|
description |
Phosphothreonine; by HASPIN and VRK1 => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:31527692
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
4)
|
chain |
C |
residue |
4 |
type |
MOD_RES |
sequence |
K
|
description |
N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708
|
source |
Swiss-Prot : SWS_FT_FI3
|
|
5)
|
chain |
C |
residue |
5 |
type |
MOD_RES |
sequence |
Q
|
description |
5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594
|
source |
Swiss-Prot : SWS_FT_FI4
|
|
6)
|
chain |
C |
residue |
6 |
type |
MOD_RES |
sequence |
T
|
description |
Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790
|
source |
Swiss-Prot : SWS_FT_FI5
|
|
7)
|
chain |
C |
residue |
8 |
type |
MOD_RES |
sequence |
R
|
description |
Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250|UniProtKB:P68433
|
source |
Swiss-Prot : SWS_FT_FI6
|
|
8)
|
chain |
C |
residue |
9 |
type |
MOD_RES |
sequence |
X
|
description |
N6-methyllysine; alternate => ECO:0000269|PubMed:11242053, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708
|
source |
Swiss-Prot : SWS_FT_FI7
|
|
9)
|
chain |
C |
residue |
10 |
type |
MOD_RES |
sequence |
S
|
description |
Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16457588
|
source |
Swiss-Prot : SWS_FT_FI8
|
|
10)
|
chain |
C |
residue |
11 |
type |
MOD_RES |
sequence |
T
|
description |
Phosphothreonine; by PKC and CHEK1 => ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:18066052, ECO:0000269|PubMed:18243098, ECO:0000269|PubMed:22901803
|
source |
Swiss-Prot : SWS_FT_FI9
|
|
|
|