|
|
eF-site ID
|
2l1c_7-AB |
|
PDB Code
|
2l1c |
|
Model
|
7 |
|
Chain
|
A, B |
|
click to enlarge
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Title
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Shc-PTB:biphosphorylated integrin beta3 cytoplasmic tail complex (1:1) |
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Classification
|
CELL ADHESION |
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Compound
|
SHC (Src homology 2 domain containing) transforming protein 1, isoform CRA_d |
|
Source
|
null (ITB3_HUMAN) |
|
|
Sequence
|
A: |
GQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRY
MGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGAT
RRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAA
DCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRA
CHILECPEGLAQDVISTIGQAFELRFKQYLR
|
| B: |
RAKWDTANNPLXKEATSTFTNITXRGT
|
|
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Description
|
(1) |
SHC (Src homology 2 domain containing) transforming protein 1, isoform CRA_d, Integrin beta-3
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
759 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine => ECO:0000269|PubMed:8631894
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
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2)
|
chain |
B |
| residue |
741 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine => ECO:0000250|UniProtKB:O54890
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
B |
| residue |
747 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine => ECO:0000269|PubMed:19141530, ECO:0007744|PubMed:18088087
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
B |
| residue |
753 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine; by PDPK1 and PKB/AKT1; in vitro => ECO:0000269|PubMed:10896934
|
| source |
Swiss-Prot : SWS_FT_FI3
|
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