|
eF-site ID
|
2l0j_5-C |
PDB Code
|
2l0j |
Model
|
5 |
Chain
|
C |
|
click to enlarge
|
|
Title
|
Solid State NMR structure of the M2 proton channel from Influenza A Virus in hydrated lipid bilayer |
Classification
|
TRANSPORT PROTEIN |
Compound
|
Matrix protein 2 |
Source
|
Influenza A virus (strain A/Udorn/307/1972 H3N2) (M2_I72A2) |
|
Sequence
|
C: |
SSDPLVVAASIIGILHLILWILDRLFFKSIYRFFEHGLKR
G
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
C |
residue |
23-43 |
type |
TRANSMEM |
sequence |
SDPLVVAASIIGILHLILWIL
|
description |
Helical; Signal-anchor for type III membrane protein => ECO:0000255|HAMAP-Rule:MF_04069
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
2)
|
chain |
C |
residue |
37 |
type |
SITE |
sequence |
H
|
description |
Essential for channel activity, possibly by being protonated during channel activation, and by forming the channel gate and the selective filter => ECO:0000255|HAMAP-Rule:MF_04069
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
3)
|
chain |
C |
residue |
41 |
type |
SITE |
sequence |
W
|
description |
Seems to be involved in pH gating => ECO:0000255|HAMAP-Rule:MF_04069
|
source |
Swiss-Prot : SWS_FT_FI3
|
|
4)
|
chain |
C |
residue |
50 |
type |
LIPID |
sequence |
S
|
description |
S-palmitoyl cysteine; by host => ECO:0000255|HAMAP-Rule:MF_04069
|
source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|