eF-site ID 2ks9_1-B PDB Code 2ks9 Model 1 Chain B click to enlarge Title Solution conformation of substance P in water complexed with NK1R Classification NEUROPEPTIDE RECEPTOR/NEUROPEPTIDE Compound Substance-P receptor Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence B:  RPKPQQFFGLM Description (1)  Substance-P receptor, Substance P Functional site 1) chain B residue 366 type SITE sequence P description Cleavage; by FAP => ECO:0000269|PubMed:21314817 source Swiss-Prot : SWS_FT_FI1 2) chain B residue 371 type SITE sequence F description Cleavage; by MME => ECO:0000269|PubMed:6208535 source Swiss-Prot : SWS_FT_FI2 3) chain B residue 370 type SITE sequence Q description Cleavage; by MME => ECO:0000269|PubMed:6208535 source Swiss-Prot : SWS_FT_FI2 4) chain B residue 372 type SITE sequence F description Cleavage; by ACE => ECO:0000269|PubMed:6208535 source Swiss-Prot : SWS_FT_FI3 5) chain B residue 373 type SITE sequence G description Cleavage; by ACE and MME => ECO:0000269|PubMed:6208535 source Swiss-Prot : SWS_FT_FI4 6) chain B residue 375 type MOD_RES sequence M description Methionine amide => ECO:0000269|PubMed:3770210 source Swiss-Prot : SWS_FT_FI5 7) chain B residue 371-375 type prosite sequence FFGLM description TACHYKININ Tachykinin family signature. FFGLM source prosite : PS00267

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