eF-site ID 2jsd_19-A
PDB Code 2jsd
Model 19
Chain A

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Title Solution structure of MMP20 complexed with NNGH
Classification HYDROLASE
Compound Matrix metalloproteinase-20
Source Homo sapiens (Human) (MMP20_HUMAN)
Sequence A:  GEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSA
VPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHA
FAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHAL
GLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGP
Description


Functional site

1) chain A
residue 183
type
sequence D
description BINDING SITE FOR RESIDUE CA A 273
source : AC1

2) chain A
residue 184
type
sequence G
description BINDING SITE FOR RESIDUE CA A 273
source : AC1

3) chain A
residue 186
type
sequence R
description BINDING SITE FOR RESIDUE CA A 273
source : AC1

4) chain A
residue 188
type
sequence T
description BINDING SITE FOR RESIDUE CA A 273
source : AC1

5) chain A
residue 206
type
sequence D
description BINDING SITE FOR RESIDUE CA A 273
source : AC1

6) chain A
residue 209
type
sequence E
description BINDING SITE FOR RESIDUE CA A 273
source : AC1

7) chain A
residue 164
type
sequence E
description BINDING SITE FOR RESIDUE CA A 274
source : AC2

8) chain A
residue 165
type
sequence A
description BINDING SITE FOR RESIDUE CA A 274
source : AC2

9) chain A
residue 166
type
sequence D
description BINDING SITE FOR RESIDUE CA A 274
source : AC2

10) chain A
residue 197
type
sequence E
description BINDING SITE FOR RESIDUE CA A 274
source : AC2

11) chain A
residue 198
type
sequence G
description BINDING SITE FOR RESIDUE CA A 274
source : AC2

12) chain A
residue 200
type
sequence G
description BINDING SITE FOR RESIDUE CA A 274
source : AC2

13) chain A
residue 202
type
sequence D
description BINDING SITE FOR RESIDUE CA A 274
source : AC2

14) chain A
residue 176
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 275
source : AC3

15) chain A
residue 178
type
sequence D
description BINDING SITE FOR RESIDUE ZN A 275
source : AC3

16) chain A
residue 191
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 275
source : AC3

17) chain A
residue 204
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 275
source : AC3

18) chain A
residue 226
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 276
source : AC4

19) chain A
residue 230
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 276
source : AC4

20) chain A
residue 236
type
sequence H
description BINDING SITE FOR RESIDUE ZN A 276
source : AC4

21) chain A
residue 187
type
sequence G
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

22) chain A
residue 188
type
sequence T
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

23) chain A
residue 189
type
sequence L
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

24) chain A
residue 190
type
sequence A
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

25) chain A
residue 222
type
sequence T
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

26) chain A
residue 226
type
sequence H
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

27) chain A
residue 227
type
sequence E
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

28) chain A
residue 230
type
sequence H
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

29) chain A
residue 236
type
sequence H
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

30) chain A
residue 245
type
sequence Y
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

31) chain A
residue 246
type
sequence P
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

32) chain A
residue 247
type
sequence T
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

33) chain A
residue 248
type
sequence Y
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

34) chain A
residue 249
type
sequence K
description BINDING SITE FOR RESIDUE NGH A 277
source : AC5

35) chain A
residue 164
type BINDING
sequence E
description
source Swiss-Prot : SWS_FT_FI2

36) chain A
residue 191
type BINDING
sequence H
description
source Swiss-Prot : SWS_FT_FI2

37) chain A
residue 197
type BINDING
sequence E
description
source Swiss-Prot : SWS_FT_FI2

38) chain A
residue 198
type BINDING
sequence G
description
source Swiss-Prot : SWS_FT_FI2

39) chain A
residue 200
type BINDING
sequence G
description
source Swiss-Prot : SWS_FT_FI2

40) chain A
residue 202
type BINDING
sequence D
description
source Swiss-Prot : SWS_FT_FI2

41) chain A
residue 204
type BINDING
sequence H
description
source Swiss-Prot : SWS_FT_FI2

42) chain A
residue 206
type BINDING
sequence D
description
source Swiss-Prot : SWS_FT_FI2

43) chain A
residue 209
type BINDING
sequence E
description
source Swiss-Prot : SWS_FT_FI2

44) chain A
residue 226
type BINDING
sequence H
description
source Swiss-Prot : SWS_FT_FI2

45) chain A
residue 230
type BINDING
sequence H
description
source Swiss-Prot : SWS_FT_FI2

46) chain A
residue 165
type BINDING
sequence A
description
source Swiss-Prot : SWS_FT_FI2

47) chain A
residue 236
type BINDING
sequence H
description
source Swiss-Prot : SWS_FT_FI2

48) chain A
residue 166
type BINDING
sequence D
description
source Swiss-Prot : SWS_FT_FI2

49) chain A
residue 176
type BINDING
sequence H
description
source Swiss-Prot : SWS_FT_FI2

50) chain A
residue 178
type BINDING
sequence D
description
source Swiss-Prot : SWS_FT_FI2

51) chain A
residue 183
type BINDING
sequence D
description
source Swiss-Prot : SWS_FT_FI2

52) chain A
residue 184
type BINDING
sequence G
description
source Swiss-Prot : SWS_FT_FI2

53) chain A
residue 186
type BINDING
sequence R
description
source Swiss-Prot : SWS_FT_FI2

54) chain A
residue 188
type BINDING
sequence T
description
source Swiss-Prot : SWS_FT_FI2

55) chain A
residue 227
type ACT_SITE
sequence E
description ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10095
source Swiss-Prot : SWS_FT_FI1

56) chain A
residue 223-232
type prosite
sequence VAAHEFGHAL
description ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAAHEFGHAL
source prosite : PS00142


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