eF-site ID 2jkz-ABCD PDB Code 2jkz Chain A, B, C, D click to enlarge Title SACCHAROMYCES CEREVISIAE HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH GMP (GUANOSINE 5'- MONOPHOSPHATE) (ORTHORHOMBIC CRYSTAL FORM) Classification TRANSFERASE Compound HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE Source (HPRT_YEAST) Sequence A:  DKQYISYNNVHQLCQVSAERIKNFKPDLIIAIGGGGFIPA RILRTFLKEPGVPTIRIFAIILSLYEDVKVSRTQWIDYEQ CKLDLVGKNVLIVDEVDDTRTTLHYALSELEKDAAEQAKA KGIDTEKSPEMKTNFGIFVLHDKQKPKKADLPAEMLNDKN RYFAAKTVPDKWYAYPWESTDIVFHTRMAIEQGNDIFIPE Q B:  DKQYISYNNVHQLCQVSAERIKNFKPDLIIAIGGGGFIPA RILRTFLKEPGVPTIRIFAIILSLYEDVKVSRTQWIDYEQ CKLDLVGKNVLIVDEVDDTRTTLHYALSELEKDAAEQAKA KGIDTEKSPEMKTNFGIFVLHDKQKPKKADLPAEMLNDKN RYFAAKTVPDKWYAYPWESTDIVFHTRMAIEQGNDIFIPE Q C:  DKQYISYNNVHQLCQVSAERIKNFKPDLIIAIGGGGFIPA RILRTFLKEPGVPTIRIFAIILSLYEDVKVSRTQWIDYEQ CKLDLVGKNVLIVDEVDDTRTTLHYALSELEKDAAEQAKA KGIDTEKSPEMKTNFGIFVLHDKQKPKKADLPAEMLNDKN RYFAAKTVPDKWYAYPWESTDIVFHTRMAIEQGNDIFIPE Q D:  DKQYISYNNVHQLCQVSAERIKNFKPDLIIAIGGGGFIPA RILRTFLKEPGVPTIRIFAIILSLYEDVKVSRTQWIDYEQ CKLDLVGKNVLIVDEVDDTRTTLHYALSELEKDAAEQAKA KGIDTEKSPEMKTNFGIFVLHDKQKPKKADLPAEMLNDKN RYFAAKTVPDKWYAYPWESTDIVFHTRMAIEQGNDIFIPE Q Description Functional site 1) chain A residue 110 type sequence D description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 2) chain A residue 111 type sequence E description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 3) chain A residue 114 type sequence D description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 4) chain A residue 115 type sequence T description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 5) chain A residue 116 type sequence R description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 6) chain A residue 117 type sequence T description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 7) chain A residue 118 type sequence T description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 8) chain A residue 159 type sequence K description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 9) chain A residue 187 type sequence K description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 10) chain A residue 188 type sequence W description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 11) chain A residue 189 type sequence Y description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 12) chain A residue 191 type sequence Y description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 13) chain A residue 194 type sequence E description BINDING SITE FOR RESIDUE 5GP A 300 source : AC1 14) chain A residue 38 type sequence G description BINDING SITE FOR RESIDUE SO4 A 301 source : AC2 15) chain A residue 39 type sequence G description BINDING SITE FOR RESIDUE SO4 A 301 source : AC2 16) chain B residue 45 type sequence R description BINDING SITE FOR RESIDUE SO4 A 301 source : AC2 17) chain B residue 48 type sequence R description BINDING SITE FOR RESIDUE SO4 A 301 source : AC2 18) chain B residue 110 type sequence D description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 19) chain B residue 111 type sequence E description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 20) chain B residue 114 type sequence D description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 21) chain B residue 115 type sequence T description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 22) chain B residue 116 type sequence R description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 23) chain B residue 117 type sequence T description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 24) chain B residue 118 type sequence T description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 25) chain B residue 159 type sequence K description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 26) chain B residue 187 type sequence K description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 27) chain B residue 188 type sequence W description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 28) chain B residue 189 type sequence Y description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 29) chain B residue 191 type sequence Y description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 30) chain B residue 194 type sequence E description BINDING SITE FOR RESIDUE 5GP B 300 source : AC3 31) chain A residue 45 type sequence R description BINDING SITE FOR RESIDUE SO4 B 301 source : AC4 32) chain A residue 48 type sequence R description BINDING SITE FOR RESIDUE SO4 B 301 source : AC4 33) chain B residue 38 type sequence G description BINDING SITE FOR RESIDUE SO4 B 301 source : AC4 34) chain B residue 39 type sequence G description BINDING SITE FOR RESIDUE SO4 B 301 source : AC4 35) chain C residue 110 type sequence D description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 36) chain C residue 111 type sequence E description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 37) chain C residue 114 type sequence D description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 38) chain C residue 115 type sequence T description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 39) chain C residue 116 type sequence R description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 40) chain C residue 117 type sequence T description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 41) chain C residue 118 type sequence T description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 42) chain C residue 159 type sequence K description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 43) chain C residue 187 type sequence K description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 44) chain C residue 188 type sequence W description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 45) chain C residue 189 type sequence Y description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 46) chain C residue 191 type sequence Y description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 47) chain C residue 194 type sequence E description BINDING SITE FOR RESIDUE 5GP C 300 source : AC5 48) chain C residue 38 type sequence G description BINDING SITE FOR RESIDUE SO4 C 301 source : AC6 49) chain C residue 39 type sequence G description BINDING SITE FOR RESIDUE SO4 C 301 source : AC6 50) chain D residue 45 type sequence R description BINDING SITE FOR RESIDUE SO4 C 301 source : AC6 51) chain D residue 48 type sequence R description BINDING SITE FOR RESIDUE SO4 C 301 source : AC6 52) chain D residue 110 type sequence D description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 53) chain D residue 111 type sequence E description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 54) chain D residue 114 type sequence D description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 55) chain D residue 115 type sequence T description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 56) chain D residue 116 type sequence R description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 57) chain D residue 117 type sequence T description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 58) chain D residue 118 type sequence T description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 59) chain D residue 159 type sequence K description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 60) chain D residue 187 type sequence K description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 61) chain D residue 188 type sequence W description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 62) chain D residue 189 type sequence Y description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 63) chain D residue 191 type sequence Y description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 64) chain D residue 194 type sequence E description BINDING SITE FOR RESIDUE 5GP D 300 source : AC7 65) chain C residue 45 type sequence R description BINDING SITE FOR RESIDUE SO4 D 301 source : AC8 66) chain C residue 48 type sequence R description BINDING SITE FOR RESIDUE SO4 D 301 source : AC8 67) chain D residue 38 type sequence G description BINDING SITE FOR RESIDUE SO4 D 301 source : AC8 68) chain D residue 39 type sequence G description BINDING SITE FOR RESIDUE SO4 D 301 source : AC8 69) chain A residue 114 type ACT_SITE sequence D description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 70) chain B residue 114 type ACT_SITE sequence D description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 71) chain C residue 114 type ACT_SITE sequence D description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 72) chain D residue 114 type ACT_SITE sequence D description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 73) chain A residue 85 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 74) chain C residue 110 type BINDING sequence D description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 75) chain C residue 159 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 76) chain C residue 188 type BINDING sequence W description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 77) chain D residue 85 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 78) chain D residue 110 type BINDING sequence D description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 79) chain D residue 159 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 80) chain D residue 188 type BINDING sequence W description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 81) chain A residue 110 type BINDING sequence D description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 82) chain A residue 159 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 83) chain A residue 188 type BINDING sequence W description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 84) chain B residue 85 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 85) chain B residue 110 type BINDING sequence D description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 86) chain B residue 159 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 87) chain B residue 188 type BINDING sequence W description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2 88) chain C residue 85 type BINDING sequence K description BINDING => ECO:0000269|PubMed:18245832 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links