eF-site ID 2jkp-B PDB Code 2jkp Chain B click to enlarge Title Structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron in complex with castanospermine Classification HYDROLASE Compound ALPHA-GLUCOSIDASE (ALPHA-GLUCOSIDASE SUSB) Source Bacteroides thetaiotaomicron (P71094_BACTN) Sequence B:  QQKLTSPDNNLVMTFQVDSKGAPTYELTYKNKVVIKPSTL GLELKKEDSKTNLYDGFEVKDTQTATFDETWQPVWGEEKE IRNHYNELAVTLYQPMNDRSIVIRFRLFNDGLGFRYEFPQ QKSLNYFVIKEEHSQFGMNGDHIAFWIPGDYDTQEYDYTI SRLSEIRGLMKEAITPNSSQTPFSQTGVQTALMMKTDDGL YINLHEAALVDYSCMHLNLDDKNMVFESWLTPDAKGDKGY MQTPCNTPWRTIIVSDDARNILASRITLNLNEPCKIADAA SWVKPVKYIGVWWDMITGKGSWAYTDELTSVKLGETDYSK TKPNGKHSANTANVKRYIDFAAAHGFDAVLVEGWNEGWED WFGNSKDYVFDFVTPYPDFDVKEIHRYAARKGIKMMMHHE TSASVRNYERHMDKAYQFMADNGYNSVKSGYVGNIIPRGE HHYGQWMNNHYLYAVKKAADYKIMVNAHEATRPTGICRTY PNLIGNESARGTEYESFGGNKVYHTTILPFTRLVGGPMDY TPGIFETHCNKMNPANNSQVRSTIARQLALYVTMYSPLQM AADIPENYERFMDAFQFIKDVALDWDETNYLEAEPGEYIT IARKAKDTDDWYVGCTAGENGHTSKLVFDFLTPGKQYIAT VYADAKDADWKENPQAYTIKKGILTNKSKLNLHAANGGGY AISIKEV Description Functional site 1) chain B residue 331 type sequence W description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 2) chain B residue 335 type sequence I description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 3) chain B residue 341 type sequence W description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 4) chain B residue 391 type sequence E description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 5) chain B residue 397 type sequence W description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 6) chain B residue 400 type sequence W description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 7) chain B residue 437 type sequence H description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 8) chain B residue 439 type sequence E description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 9) chain B residue 467 type sequence K description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 10) chain B residue 471 type sequence V description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 11) chain B residue 507 type sequence H description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 12) chain B residue 508 type sequence E description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 13) chain B residue 526 type sequence E description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 14) chain B residue 532 type sequence E description BINDING SITE FOR RESIDUE CTS B1727 source : AC2 15) chain B residue 194 type sequence E description BINDING SITE FOR RESIDUE CA B1728 source : AC3 16) chain B residue 508 type sequence E description BINDING SITE FOR RESIDUE CA B1728 source : AC3 17) chain B residue 526 type sequence E description BINDING SITE FOR RESIDUE CA B1728 source : AC3 18) chain B residue 532 type sequence E description BINDING SITE FOR RESIDUE CA B1728 source : AC3 19) chain B residue 112 type sequence P description BINDING SITE FOR RESIDUE EDO B1729 source : AC7 20) chain B residue 113 type sequence V description BINDING SITE FOR RESIDUE EDO B1729 source : AC7 21) chain B residue 114 type sequence W description BINDING SITE FOR RESIDUE EDO B1729 source : AC7 22) chain B residue 516 type sequence C description BINDING SITE FOR RESIDUE EDO B1729 source : AC7 23) chain B residue 520 type sequence P description BINDING SITE FOR RESIDUE EDO B1729 source : AC7 24) chain B residue 333 type sequence D description BINDING SITE FOR RESIDUE EDO B1730 source : AC8 25) chain B residue 338 type sequence K description BINDING SITE FOR RESIDUE EDO B1730 source : AC8 26) chain B residue 372 type sequence N description BINDING SITE FOR RESIDUE EDO B1730 source : AC8 27) chain B residue 376 type sequence Y description BINDING SITE FOR RESIDUE EDO B1730 source : AC8 28) chain B residue 194 type SITE sequence E description Substrate source Swiss-Prot : SWS_FT_FI4 29) chain B residue 331 type SITE sequence W description Substrate source Swiss-Prot : SWS_FT_FI4 30) chain B residue 467 type SITE sequence K description Substrate source Swiss-Prot : SWS_FT_FI4 31) chain B residue 194 type BINDING sequence E description BINDING => ECO:0000269|PubMed:18981178 source Swiss-Prot : SWS_FT_FI2 32) chain B residue 508 type BINDING sequence E description BINDING => ECO:0000269|PubMed:18981178 source Swiss-Prot : SWS_FT_FI2 33) chain B residue 526 type BINDING sequence E description BINDING => ECO:0000269|PubMed:18981178 source Swiss-Prot : SWS_FT_FI2 34) chain B residue 532 type BINDING sequence E description BINDING => ECO:0000269|PubMed:18981178 source Swiss-Prot : SWS_FT_FI2 35) chain B residue 215 type BINDING sequence P description source Swiss-Prot : SWS_FT_FI3 36) chain B residue 437 type BINDING sequence H description source Swiss-Prot : SWS_FT_FI3 37) chain B residue 507 type BINDING sequence H description source Swiss-Prot : SWS_FT_FI3 38) chain B residue 532 type ACT_SITE sequence E description Proton donor/acceptor => ECO:0000305|PubMed:18981178 source Swiss-Prot : SWS_FT_FI1

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