eF-site ID 2jgd-AB PDB Code 2jgd Chain A, B click to enlarge Title E. COLI 2-oxoglutarate dehydrogenase (E1o) Classification OXIDOREDUCTASE Compound 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT Source (ODO1_ECOLI) Sequence A:  DTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDDLDPS FHDLTEDFQETFNVGSFAETMKLGELLEALKQTYCGPIGA EYMHITSTEEKRWIQQRIESRATFNSEEKKRFLSELTAAE GLERYLGAKFPGRFSLEGGDALIPMLKEMIRHAGNSGTRE VVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHHLGTGDV KYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVR ARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKA RGYEVGGTVRIVINNQYCTDIGKMVQAPIFHVNADDPEAV AFVTRLALDFRNTFKRDVFIDLVCYRRHQPLMYQKIKKHP TPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVA EWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRI STVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAY ATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTP LQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTI WEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHG YEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHML RRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLP AIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVA IVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGA WYCSQHHFREVIPFGASLRYAGRPASASPAVGHMSVHQKQ QQDLVNDALNVE B:  TNVKQVKVLQLINAYRFRGHQHANLDPLGLWKVADLDPSF HDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGP IGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSEL TAAEGLERYLGAKFPRFSLEGGDALIPMLKEMIRHAGNSG TREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHGTGD VKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSV RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSK ARGYEVGGTVRIVINNQYCTDIGKMVQAPIFHVNADDPEA VAFVTRLALDFRNTFKRDVFIDLVCYRRHYQKIKKHPTPR KIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWR PMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTV PEAVEMQSRVAKIYADRQAMAAGEKLFDWGGAENLAYATL VDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQH IHNGQGAFRVWDSSEEAVLAFEYGYATAEPRTLTIWEAQF GDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQG PEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQAL RGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAIGEI DELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIE QLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQ HHFREVIPFGASLRYAGRPASASPAVGYMSVHQKQQQDLV NDALNVE Description (1)  2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT (E.C.1.2.4.2) Functional site 1) chain A residue 302 type sequence S description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 2) chain A residue 313 type sequence H description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 3) chain A residue 315 type sequence A description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 4) chain A residue 337 type sequence R description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 5) chain A residue 526 type sequence M description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 6) chain A residue 530 type sequence S description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 7) chain A residue 531 type sequence F description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 8) chain A residue 533 type sequence W description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 9) chain A residue 673 type sequence T description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 10) chain A residue 709 type sequence G description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 11) chain A residue 710 type sequence R description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 12) chain A residue 711 type sequence M description BINDING SITE FOR RESIDUE AMP A1934 source : AC1 13) chain B residue 302 type sequence S description BINDING SITE FOR RESIDUE AMP B1934 source : AC2 14) chain B residue 313 type sequence H description BINDING SITE FOR RESIDUE AMP B1934 source : AC2 15) chain B residue 315 type sequence A description BINDING SITE FOR RESIDUE AMP B1934 source : AC2 16) chain B residue 337 type sequence R description BINDING SITE FOR RESIDUE AMP B1934 source : AC2 17) chain B residue 530 type sequence S description BINDING SITE FOR RESIDUE AMP B1934 source : AC2 18) chain B residue 531 type sequence F description BINDING SITE FOR RESIDUE AMP B1934 source : AC2 19) chain B residue 533 type sequence W description BINDING SITE FOR RESIDUE AMP B1934 source : AC2 20) chain B residue 673 type sequence T description BINDING SITE FOR RESIDUE AMP B1934 source : AC2 21) chain B residue 709 type sequence G description BINDING SITE FOR RESIDUE AMP B1934 source : AC2 22) chain B residue 710 type sequence R description BINDING SITE FOR RESIDUE AMP B1934 source : AC2 23) chain B residue 711 type sequence M description BINDING SITE FOR RESIDUE AMP B1934 source : AC2

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