|
|
eF-site ID
|
2jgc-A |
|
PDB Code
|
2jgc |
|
Chain
|
A |
|
click to enlarge
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Title
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Structure of the human eIF4E homologous protein, 4EHP without ligand bound |
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Classification
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TRANSLATION |
|
Compound
|
EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2 |
|
Source
|
null (4EBP1_HUMAN) |
|
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Sequence
|
A: |
VVPGPAEHPLQYNYTFWYSRRTPGRQNIKQIGTFASVEQF
WRFYSHMVRPGDLTGHSDFHLFKEGIKPMWEDDANKNGGK
WIIRLRKGLASRCWENLILAMLGEQFMVGEEICGAVVSVR
FQEDIISIWNKTASDQATTARIRDTLRRVLNLPPNTIMEY
KTHTDGPQRLLF
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Description
|
|
Functional site
|
|
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1)
|
chain |
A |
| residue |
124 |
| type |
MOD_RES |
| sequence |
W
|
| description |
Phosphotyrosine => ECO:0007744|PubMed:18669648
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
A |
| residue |
174 |
| type |
MOD_RES |
| sequence |
R
|
| description |
Phosphotyrosine => ECO:0007744|PubMed:18669648
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
A |
| residue |
112-135 |
| type |
prosite |
| sequence |
DFHLFKEGIKPMWEDDANKNGGKW
|
| description |
IF4E Eukaryotic initiation factor 4E signature. DFhlFKegIkPmWEDdanknGGKW
|
| source |
prosite : PS00813
|
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