|
|
eF-site ID
|
2jgb-B |
|
PDB Code
|
2jgb |
|
Chain
|
B |
|
click to enlarge
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Title
|
Structure of human eIF4E homologous protein 4EHP with m7GTP |
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Classification
|
TRANSLATION |
|
Compound
|
EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2 |
|
Source
|
null (4EBP1_HUMAN) |
|
|
Sequence
|
B: |
RIIYDRKFLMECRNSP
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
51 |
| type |
MOD_RES |
| sequence |
R
|
| description |
Phosphothreonine => ECO:0007744|PubMed:18220336, ECO:0007744|PubMed:18669648
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
55 |
| type |
MOD_RES |
| sequence |
D
|
| description |
Phosphotyrosine => ECO:0007744|PubMed:18669648
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
B |
| residue |
66 |
| type |
MOD_RES |
| sequence |
P
|
| description |
Phosphoserine; by DYRK2, MAPK1, MAPK3 and MTOR => ECO:0000269|PubMed:12588975, ECO:0000269|PubMed:12747827, ECO:0000269|PubMed:22578813, ECO:0000269|PubMed:25702871, ECO:0000269|PubMed:29750193, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
B |
| residue |
58 |
| type |
CROSSLNK |
| sequence |
F
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:22578813
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|