eF-site ID 2jcn-A PDB Code 2jcn Chain A click to enlarge Title The crystal structure of BAK1 - a mitochondrial apoptosis regulator Classification APOPTOSIS Compound BCL-2 HOMOLOGOUS ANTAGONIST/KILLER Source (BAK_HUMAN) Sequence A:  SEEQVAQDTEEVFRSYVFYRHQQEQEAPADPEMVTLPLQP SSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENA YEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGL TGFLGQVTRFVVDFMLHHCIARWIAQRGGWVAALNLG Description (1)  BCL-2 HOMOLOGOUS ANTAGONIST/KILLER Functional site 1) chain A residue 124 type sequence N description BINDING SITE FOR RESIDUE SO4 A1001 source : AC1 2) chain A residue 125 type sequence W description BINDING SITE FOR RESIDUE SO4 A1001 source : AC1 3) chain A residue 152 type sequence G description BINDING SITE FOR RESIDUE SO4 A1001 source : AC1 4) chain A residue 156 type sequence R description BINDING SITE FOR RESIDUE SO4 A1001 source : AC1 5) chain A residue 170 type sequence W description BINDING SITE FOR RESIDUE SO4 A1001 source : AC1 6) chain A residue 174 type sequence R description BINDING SITE FOR RESIDUE SO4 A1001 source : AC1 7) chain A residue 118-136 type prosite sequence LFESGINWGRVVALLGFGY description BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFeSGi.NWGRVVALLgFGY source prosite : PS01080 8) chain A residue 170-181 type prosite sequence WIAQRGGWVAAL description BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIaqrGGWVaAL source prosite : PS01258 9) chain A residue 74-88 type prosite sequence VGRQLAIIGDDINRR description BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VgrqLAiIGDDINRR source prosite : PS01259 10) chain A residue 160 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 11) chain A residue 164 type BINDING sequence H description source Swiss-Prot : SWS_FT_FI1

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