eF-site ID 2jc5-A PDB Code 2jc5 Chain A click to enlarge Title Apurinic Apyrimidinic (AP) endonuclease (NApe) from Neisseria Meningitidis Classification HYDROLASE Compound EXODEOXYRIBONUCLEASE Source (Q7DD47_NEIMB) Sequence A:  MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQ EADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNV QIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQ QVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLK NWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVP GYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYK DEKFSDHAPLVVEYDYAAE Description Functional site 1) chain A residue 10 type sequence N description BINDING SITE FOR RESIDUE MG A1260 source : AC1 2) chain A residue 36 type sequence E description BINDING SITE FOR RESIDUE MG A1260 source : AC1 3) chain A residue 112 type sequence S description BINDING SITE FOR RESIDUE BCN A1261 source : AC2 4) chain A residue 113 type sequence G description BINDING SITE FOR RESIDUE BCN A1261 source : AC2 5) chain A residue 114 type sequence S description BINDING SITE FOR RESIDUE BCN A1261 source : AC2 6) chain A residue 123 type sequence K description BINDING SITE FOR RESIDUE BCN A1261 source : AC2 7) chain A residue 151 type sequence N description BINDING SITE FOR RESIDUE BCN A1261 source : AC2 8) chain A residue 169 type sequence S description BINDING SITE FOR RESIDUE BCN A1261 source : AC2 9) chain A residue 228 type sequence E description BINDING SITE FOR RESIDUE BCN A1261 source : AC2 10) chain A residue 124 type sequence Y description BINDING SITE FOR RESIDUE DIO A1264 source : AC3 11) chain A residue 174 type sequence E description BINDING SITE FOR RESIDUE DIO A1264 source : AC3 12) chain A residue 16 type sequence Y description BINDING SITE FOR RESIDUE DIO A1265 source : AC4 13) chain A residue 21 type sequence Y description BINDING SITE FOR RESIDUE DIO A1265 source : AC4 14) chain A residue 47 type sequence D description BINDING SITE FOR RESIDUE DIO A1265 source : AC4 15) chain A residue 30 type sequence D description BINDING SITE FOR RESIDUE GOL A1262 source : AC5 16) chain A residue 31 type sequence I description BINDING SITE FOR RESIDUE GOL A1262 source : AC5 17) chain A residue 74 type sequence K description BINDING SITE FOR RESIDUE GOL A1262 source : AC5 18) chain A residue 75 type sequence R description BINDING SITE FOR RESIDUE GOL A1262 source : AC5 19) chain A residue 100 type sequence F description BINDING SITE FOR RESIDUE GOL A1262 source : AC5 20) chain A residue 258 type sequence A description BINDING SITE FOR RESIDUE GOL A1262 source : AC5 21) chain A residue 212 type sequence Y description BINDING SITE FOR RESIDUE GOL A1263 source : AC6 22) chain A residue 215 type sequence D description BINDING SITE FOR RESIDUE GOL A1263 source : AC6 23) chain A residue 240 type sequence K description BINDING SITE FOR RESIDUE GOL A1263 source : AC6 24) chain A residue 29-38 type prosite sequence ADIVCVQELK description AP_NUCLEASE_F1_1 AP endonucleases family 1 signature 1. ADIVCVQELK source prosite : PS00726

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