eF-site ID 2jam-A PDB Code 2jam Chain A click to enlarge Title Crystal structure of human calmodulin-dependent protein kinase I G Classification TRANSFERASE Compound CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G Source ORGANISM_SCIENTIFIC: UNIDENTIFIED; Sequence A:  NIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKS SLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGG ELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRD LKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACGTP GYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEET ESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPN ERYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNFAKS Description Functional site 1) chain A residue 285 type sequence H description BINDING SITE FOR RESIDUE CA A 1306 source : AC1 2) chain A residue 52 type sequence K description BINDING SITE FOR RESIDUE EDO A 1304 source : AC2 3) chain A residue 164 type sequence T description BINDING SITE FOR RESIDUE EDO A 1304 source : AC2 4) chain A residue 165 type sequence D description BINDING SITE FOR RESIDUE EDO A 1304 source : AC2 5) chain A residue 166 type sequence F description BINDING SITE FOR RESIDUE EDO A 1304 source : AC2 6) chain A residue 169 type sequence S description BINDING SITE FOR RESIDUE EDO A 1304 source : AC2 7) chain A residue 29 type sequence L description BINDING SITE FOR RESIDUE J60 A 1305 source : AC3 8) chain A residue 37 type sequence V description BINDING SITE FOR RESIDUE J60 A 1305 source : AC3 9) chain A residue 50 type sequence A description BINDING SITE FOR RESIDUE J60 A 1305 source : AC3 10) chain A residue 52 type sequence K description BINDING SITE FOR RESIDUE J60 A 1305 source : AC3 11) chain A residue 98 type sequence M description BINDING SITE FOR RESIDUE J60 A 1305 source : AC3 12) chain A residue 99 type sequence Q description BINDING SITE FOR RESIDUE J60 A 1305 source : AC3 13) chain A residue 100 type sequence L description BINDING SITE FOR RESIDUE J60 A 1305 source : AC3 14) chain A residue 101 type sequence V description BINDING SITE FOR RESIDUE J60 A 1305 source : AC3 15) chain A residue 151 type sequence L description BINDING SITE FOR RESIDUE J60 A 1305 source : AC3 16) chain A residue 164 type sequence T description BINDING SITE FOR RESIDUE J60 A 1305 source : AC3 17) chain A residue 165 type sequence D description BINDING SITE FOR RESIDUE J60 A 1305 source : AC3 18) chain A residue 144 type sequence D description BINDING SITE FOR RESIDUE EDO B 1304 source : AC5 19) chain A residue 201 type sequence V description BINDING SITE FOR RESIDUE EDO B 1304 source : AC5 20) chain A residue 205 type sequence S description BINDING SITE FOR RESIDUE EDO B 1304 source : AC5 21) chain A residue 144 type ACT_SITE sequence D description Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027 source Swiss-Prot : SWS_FT_FI1 22) chain A residue 29-56 type prosite sequence LGSGAFSEVFLVKQRLTGKLFALKCIKK description PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGSGAFSEVFlVkqrltgklfalk......CIKK source prosite : PS00107 23) chain A residue 140-152 type prosite sequence IVHRDLKPENLLY description PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IvHrDLKpeNLLY source prosite : PS00108 24) chain A residue 29 type BINDING sequence L description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2 25) chain A residue 52 type BINDING sequence K description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2

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