eF-site ID 2izz-E PDB Code 2izz Chain E click to enlarge Title Crystal structure of human pyrroline-5-carboxylate reductase Classification OXIDOREDUCTASE Compound PYRROLINE-5-CARBOXYLATE REDUCTASE 1 Source Homo sapiens (Human) (P5CR1_HUMAN) Sequence E:  MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLA TVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILD EIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRC MTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCT EVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRR LAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATIH ALHVLESGGFRSLLINAVEASCIRTRELQSMA Description Functional site 1) chain E residue 7 type sequence G description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 2) chain E residue 8 type sequence A description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 3) chain E residue 9 type sequence G description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 4) chain E residue 10 type sequence Q description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 5) chain E residue 11 type sequence L description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 6) chain E residue 34 type sequence S description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 7) chain E residue 35 type sequence P description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 8) chain E residue 39 type sequence L description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 9) chain E residue 56 type sequence N description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 10) chain E residue 69 type sequence A description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 11) chain E residue 70 type sequence V description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 12) chain E residue 71 type sequence K description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 13) chain E residue 72 type sequence P description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 14) chain E residue 95 type sequence C description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 15) chain E residue 96 type sequence A description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 16) chain E residue 97 type sequence A description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 17) chain E residue 122 type sequence T description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 18) chain E residue 124 type sequence T description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 19) chain E residue 231 type sequence V description BINDING SITE FOR RESIDUE NAD E 350 source : BC2 20) chain E residue 71 type sequence K description BINDING SITE FOR RESIDUE EDO E1273 source : BC3 21) chain E residue 230 type sequence N description BINDING SITE FOR RESIDUE EDO E1273 source : BC3 22) chain E residue 233 type sequence S description BINDING SITE FOR RESIDUE EDO E1273 source : BC3 23) chain E residue 6 type BINDING sequence I description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 24) chain E residue 34 type BINDING sequence S description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 25) chain E residue 56 type BINDING sequence N description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 26) chain E residue 69 type BINDING sequence A description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 27) chain E residue 95 type BINDING sequence C description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 28) chain E residue 2 type MOD_RES sequence S description N-acetylserine => ECO:0000269|Ref.8, ECO:0000269|Ref.9, ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI2

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