eF-site ID 2izz-D PDB Code 2izz Chain D click to enlarge Title Crystal structure of human pyrroline-5-carboxylate reductase Classification OXIDOREDUCTASE Compound PYRROLINE-5-CARBOXYLATE REDUCTASE 1 Source Homo sapiens (Human) (P5CR1_HUMAN) Sequence D:  LYFQSMSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSP DMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHII PFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAP RVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSS VGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKM GLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPG GATIHALHVLESGGFRSLLINAVEASCIRTRELQSM Description Functional site 1) chain D residue 230 type sequence N description BINDING SITE FOR RESIDUE NAD C 350 source : AC6 2) chain D residue 231 type sequence V description BINDING SITE FOR RESIDUE NAD C 350 source : AC6 3) chain D residue 231 type sequence V description BINDING SITE FOR RESIDUE EDO C1277 source : AC8 4) chain D residue 238 type sequence T description BINDING SITE FOR RESIDUE EDO C1277 source : AC8 5) chain D residue 8 type sequence A description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 6) chain D residue 9 type sequence G description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 7) chain D residue 10 type sequence Q description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 8) chain D residue 11 type sequence L description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 9) chain D residue 33 type sequence S description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 10) chain D residue 34 type sequence S description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 11) chain D residue 35 type sequence P description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 12) chain D residue 39 type sequence L description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 13) chain D residue 56 type sequence N description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 14) chain D residue 69 type sequence A description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 15) chain D residue 70 type sequence V description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 16) chain D residue 71 type sequence K description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 17) chain D residue 72 type sequence P description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 18) chain D residue 95 type sequence C description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 19) chain D residue 96 type sequence A description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 20) chain D residue 97 type sequence A description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 21) chain D residue 122 type sequence T description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 22) chain D residue 124 type sequence T description BINDING SITE FOR RESIDUE NAD D 350 source : AC9 23) chain D residue 230 type sequence N description BINDING SITE FOR RESIDUE EDO D1272 source : BC1 24) chain D residue 233 type sequence S description BINDING SITE FOR RESIDUE EDO D1272 source : BC1 25) chain D residue 6 type BINDING sequence I description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 26) chain D residue 34 type BINDING sequence S description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 27) chain D residue 56 type BINDING sequence N description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 28) chain D residue 69 type BINDING sequence A description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 29) chain D residue 95 type BINDING sequence C description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 30) chain D residue 2 type MOD_RES sequence S description N-acetylserine => ECO:0000269|Ref.8, ECO:0000269|Ref.9, ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI2

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