eF-site ID 2izz-B PDB Code 2izz Chain B click to enlarge Title Crystal structure of human pyrroline-5-carboxylate reductase Classification OXIDOREDUCTASE Compound PYRROLINE-5-CARBOXYLATE REDUCTASE 1 Source Homo sapiens (Human) (P5CR1_HUMAN) Sequence B:  NLYFQSMSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASS PDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAVKPHI IPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPA PRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLS SVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVK MGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSP GGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMAD Description Functional site 1) chain B residue 230 type sequence N description BINDING SITE FOR RESIDUE NAD A 350 source : AC1 2) chain B residue 231 type sequence V description BINDING SITE FOR RESIDUE NAD A 350 source : AC1 3) chain B residue 233 type sequence S description BINDING SITE FOR RESIDUE NAD A 350 source : AC1 4) chain B residue 175 type sequence G description BINDING SITE FOR RESIDUE EDO A1272 source : AC2 5) chain B residue 231 type sequence V description BINDING SITE FOR RESIDUE EDO A1273 source : AC3 6) chain B residue 238 type sequence T description BINDING SITE FOR RESIDUE EDO A1273 source : AC3 7) chain B residue 71 type sequence K description BINDING SITE FOR RESIDUE EDO A1274 source : AC4 8) chain B residue 7 type sequence G description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 9) chain B residue 8 type sequence A description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 10) chain B residue 9 type sequence G description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 11) chain B residue 10 type sequence Q description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 12) chain B residue 11 type sequence L description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 13) chain B residue 34 type sequence S description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 14) chain B residue 35 type sequence P description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 15) chain B residue 39 type sequence L description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 16) chain B residue 56 type sequence N description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 17) chain B residue 69 type sequence A description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 18) chain B residue 70 type sequence V description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 19) chain B residue 71 type sequence K description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 20) chain B residue 72 type sequence P description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 21) chain B residue 78 type sequence I description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 22) chain B residue 95 type sequence C description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 23) chain B residue 96 type sequence A description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 24) chain B residue 97 type sequence A description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 25) chain B residue 121 type sequence M description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 26) chain B residue 122 type sequence T description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 27) chain B residue 124 type sequence T description BINDING SITE FOR RESIDUE NAD B 350 source : AC5 28) chain B residue 95 type BINDING sequence C description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 29) chain B residue 6 type BINDING sequence I description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 30) chain B residue 34 type BINDING sequence S description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 31) chain B residue 56 type BINDING sequence N description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 32) chain B residue 69 type BINDING sequence A description BINDING => ECO:0000269|Ref.18 source Swiss-Prot : SWS_FT_FI1 33) chain B residue 2 type MOD_RES sequence S description N-acetylserine => ECO:0000269|Ref.8, ECO:0000269|Ref.9, ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI2

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