eF-site ID 2ix3-A
PDB Code 2ix3
Chain A

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Title Structure of yeast Elongation Factor 3
Classification TRANSLATION
Compound ELONGATION FACTOR 3
Source null (EF3A_YEAST)
Sequence A:  SDSQQSIKVLEELFQKLSVATADNRHEIASEVASFLNGNI
IEHDVPEHFFGELAKGIKDKKTAANAMQAVAHIANQSNLS
PSVEPYIVQLVPAICTNAGNKDKEIQSVASETLISIVNAV
NPVAIKALLPHLTNAIVETNKWQEKIAILAAFSAMVDAAK
DQVALRMPELIPVLSETMWDTKKEVKAAATAAMTKATETV
DNKDIERFIPSLIQCIADPTEVPETVHLLGATTFVAEVTP
ATLSIMVPLLSRGLNERETGIKRKSAVIIDNMCKLVEDPQ
VIAPFLGKLLPGLKSNFATIADPEAREVTLRALKTLRRVG
NVGEDDAIPELSHAGDVSTTLQVVNELLKDETVAPRFKIV
VEYIAAIGADLIDERIIDQQAWFTHITPYMTIFLHEKKAK
DILDEFRKRAVDNIPVGPNFDDEEDEGEDLCNCEFSLAYG
AKILLNKTQLRLKRARRYGICGPNGCGKSTLMRAIANGQV
DGFPTQEECRTVYVEHDIDGTHSDTSVLDFVFESGVGTKE
AIKDKLIEFGFTDEMIAMPISALSGGWKMKLALARAVLRN
ADILLLDEPTNHLDTVNVAWLVNYLNTCGITSITISHDSV
FLDNVCEYIINYEGLKLRKYKGNFTEFVKKCPAAKAYEEL
SNTDLEFKFPEPGYLEGVKTKQKAIVKVTNMEFQYPGTSK
PQITDINFQCSLSSRIAVIGPNGAGKSTLINVLTGELLPT
SGEVYTHENCRIAYIKQHAFAHIESHLDKTPSEYIQWRFQ
TGEDRETMDRANRQINENDAEAMNKIFKIEGTPRRIAGIH
SRRKFKNTYEYECSFLLGENIGMKSERWVPMMSVDNAWIP
RGELVESHSKMVAEVDMKEALASGQFRPLTRKEIEEHCSM
LGLDPEIVSHSRIRGLSGGQKVKLVLAAGTWQRPHLIVLD
EPTNYLDRDSLGALSKALKEFEGGVIIITHSAEFTKNLTE
EVWAVKDGRMTPS
Description (1)  ELONGATION FACTOR 3


Functional site

1) chain A
residue 43
type
sequence H
description BINDING SITE FOR RESIDUE SO4 A2973
source : AC1

2) chain A
residue 395
type
sequence H
description BINDING SITE FOR RESIDUE SO4 A2973
source : AC1

3) chain A
residue 396
type
sequence E
description BINDING SITE FOR RESIDUE SO4 A2973
source : AC1

4) chain A
residue 950
type
sequence H
description BINDING SITE FOR RESIDUE SO4 A2973
source : AC1

5) chain A
residue 544
type
sequence S
description BINDING SITE FOR RESIDUE SO4 A2974
source : AC2

6) chain A
residue 547
type
sequence W
description BINDING SITE FOR RESIDUE SO4 A2974
source : AC2

7) chain A
residue 577
type
sequence N
description BINDING SITE FOR RESIDUE SO4 A2974
source : AC2

8) chain A
residue 449
type
sequence Q
description BINDING SITE FOR RESIDUE SO4 A2975
source : AC3

9) chain A
residue 616
type
sequence K
description BINDING SITE FOR RESIDUE SO4 A2975
source : AC3

10) chain A
residue 618
type
sequence R
description BINDING SITE FOR RESIDUE SO4 A2975
source : AC3

11) chain A
residue 582
type
sequence V
description BINDING SITE FOR RESIDUE SO4 A2976
source : AC4

12) chain A
residue 583
type
sequence N
description BINDING SITE FOR RESIDUE SO4 A2976
source : AC4

13) chain A
residue 586
type
sequence N
description BINDING SITE FOR RESIDUE SO4 A2976
source : AC4

14) chain A
residue 465
type
sequence G
description BINDING SITE FOR RESIDUE SO4 A2977
source : AC5

15) chain A
residue 466
type
sequence C
description BINDING SITE FOR RESIDUE SO4 A2977
source : AC5

16) chain A
residue 467
type
sequence G
description BINDING SITE FOR RESIDUE SO4 A2977
source : AC5

17) chain A
residue 468
type
sequence K
description BINDING SITE FOR RESIDUE SO4 A2977
source : AC5

18) chain A
residue 469
type
sequence S
description BINDING SITE FOR RESIDUE SO4 A2977
source : AC5

19) chain A
residue 654
type
sequence Y
description BINDING SITE FOR RESIDUE SO4 A2978
source : AC6

20) chain A
residue 656
type
sequence E
description BINDING SITE FOR RESIDUE SO4 A2978
source : AC6

21) chain A
residue 657
type
sequence G
description BINDING SITE FOR RESIDUE SO4 A2978
source : AC6

22) chain A
residue 659
type
sequence K
description BINDING SITE FOR RESIDUE SO4 A2978
source : AC6

23) chain A
residue 518
type
sequence T
description BINDING SITE FOR RESIDUE SO4 B2977
source : BC2

24) chain A
residue 520
type
sequence E
description BINDING SITE FOR RESIDUE SO4 B2977
source : BC2

25) chain A
residue 543-557
type prosite
sequence LSGGWKMKLALARAV
description ABC_TRANSPORTER_1 ABC transporters family signature. LSGGWKMKLALARAV
source prosite : PS00211

26) chain A
residue 896-910
type prosite
sequence LSGGQKVKLVLAAGT
description ABC_TRANSPORTER_1 ABC transporters family signature. LSGGWKMKLALARAV
source prosite : PS00211

27) chain A
residue 463
type BINDING
sequence P
description BINDING => ECO:0000255|PROSITE-ProRule:PRU00434
source Swiss-Prot : SWS_FT_FI1

28) chain A
residue 701
type BINDING
sequence P
description BINDING => ECO:0000255|PROSITE-ProRule:PRU00434
source Swiss-Prot : SWS_FT_FI1

29) chain A
residue 2
type MOD_RES
sequence D
description N-acetylserine => ECO:0000269|PubMed:9298649, ECO:0007744|PubMed:22814378
source Swiss-Prot : SWS_FT_FI2

30) chain A
residue 187
type MOD_RES
sequence A
description N6,N6,N6-trimethyllysine => ECO:0000269|PubMed:22522802
source Swiss-Prot : SWS_FT_FI3

31) chain A
residue 196
type MOD_RES
sequence A
description N6,N6,N6-trimethyllysine => ECO:0000269|PubMed:22522802
source Swiss-Prot : SWS_FT_FI3

32) chain A
residue 789
type MOD_RES
sequence I
description N6,N6,N6-trimethyllysine => ECO:0000269|PubMed:22522802
source Swiss-Prot : SWS_FT_FI3

33) chain A
residue 642
type MOD_RES
sequence N
description Phosphoserine => ECO:0007744|PubMed:19779198
source Swiss-Prot : SWS_FT_FI4

34) chain A
residue 972
type MOD_RES
sequence P
description Phosphothreonine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
source Swiss-Prot : SWS_FT_FI5

35) chain A
residue 350
type CROSSLNK
sequence D
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
source Swiss-Prot : SWS_FT_FI6

36) chain A
residue 636
type CROSSLNK
sequence A
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
source Swiss-Prot : SWS_FT_FI6


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