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|
eF-site ID
|
2iw8-D |
|
PDB Code
|
2iw8 |
|
Chain
|
D |
|
click to enlarge
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Title
|
STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A F82H-L83V-H84D MUTANT WITH AN O6-CYCLOHEXYLMETHYLGUANINE INHIBITOR |
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Classification
|
CELL CYCLE |
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Compound
|
CELL DIVISION PROTEIN KINASE 2 |
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Source
|
Homo sapiens (Human) (CCNA2_HUMAN) |
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Sequence
|
D: |
YHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDW
LVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVG
TAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHL
VLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLG
ELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLI
RKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSK
YHGVSLLNPPETLNL
|
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Description
|
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Functional site
|
|
|
1)
|
chain |
D |
| residue |
192 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE SGM D1433
|
| source |
: AC4
|
|
|
2)
|
chain |
D |
| residue |
193 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE SGM D1433
|
| source |
: AC4
|
|
|
3)
|
chain |
D |
| residue |
241 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE SGM D1433
|
| source |
: AC4
|
|
|
4)
|
chain |
D |
| residue |
305 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE SGM D1433
|
| source |
: AC4
|
|
|
|