eF-site ID 2iw6-B PDB Code 2iw6 Chain B click to enlarge Title STRUCTURE OF HUMAN THR160-PHOSPHO CDK2-CYCLIN A COMPLEXED WITH A BISANILINOPYRIMIDINE INHIBITOR Classification CELL CYCLE Compound CELL DIVISION PROTEIN KINASE 2 Source Homo sapiens (Human) (CCNA2_HUMAN) Sequence B:  PDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILV DWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQL VGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRME HLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMF LGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPES LIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKN SKYHGVSLLNPPETLNL Description Functional site 1) chain B residue 200 type sequence M description BINDING SITE FOR RESIDUE MG B 1434 source : AC1 2) chain B residue 203 type sequence Q description BINDING SITE FOR RESIDUE MG B 1434 source : AC1 3) chain B residue 206 type sequence I description BINDING SITE FOR RESIDUE MG B 1434 source : AC1 4) chain B residue 189 type sequence M description BINDING SITE FOR RESIDUE SGM B 1433 source : AC4 5) chain B residue 192 type sequence K description BINDING SITE FOR RESIDUE SGM B 1433 source : AC4 6) chain B residue 193 type sequence C description BINDING SITE FOR RESIDUE SGM B 1433 source : AC4 7) chain B residue 241 type sequence R description BINDING SITE FOR RESIDUE SGM B 1433 source : AC4 8) chain B residue 211-242 type prosite sequence RAILVDWLVEVGEEYKLQNETLHLAVNYIDRF description CYCLINS Cyclins signature. RaiLvdWLvevgeeykLqnetLhlAVnYIDRF source prosite : PS00292

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