eF-site ID 2ist-A PDB Code 2ist Chain A click to enlarge Title crystal structure of RluD from E. coli Classification ISOMERASE Compound Ribosomal large subunit pseudouridine synthase D Source Escherichia coli (strain K12) (RLUD_ECOLI) Sequence A:  AQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWIL DQRVLVNGKVCDKPKEKVLGGEQVAINAEIERFEPQDIPL DIVYEDEDIIIINKPRDLVVHPGAGNPDGTVLNALLHYYP PIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQR REITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPM GKPAVTHYRIMEHFRVHTRLRLRLETGRTHQIRVHMAHIT HPLVGDPVYGGRPRPPKGASEAFISTLRKFDRQALHATML RLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVD W Description Functional site 1) chain A residue 139 type sequence D description BINDING SITE FOR RESIDUE CL A 477 source : AC1 2) chain A residue 171 type sequence Y description BINDING SITE FOR RESIDUE CL A 477 source : AC1 3) chain A residue 310 type sequence E description BINDING SITE FOR RESIDUE BCT A 803 source : AC2 4) chain A residue 313 type sequence R description BINDING SITE FOR RESIDUE BCT A 803 source : AC2 5) chain A residue 83 type sequence P description BINDING SITE FOR RESIDUE BCT A 804 source : AC3 6) chain A residue 84 type sequence L description BINDING SITE FOR RESIDUE BCT A 804 source : AC3 7) chain A residue 135-149 type prosite sequence VHRLDKDTTGLMVVA description PSI_RLU Rlu family of pseudouridine synthase signature. VHRLDkdTTGLMVVA source prosite : PS01129 8) chain A residue 140 type ACT_SITE sequence K description source Swiss-Prot : SWS_FT_FI1

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