|
|
eF-site ID
|
2iik-B |
|
PDB Code
|
2iik |
|
Chain
|
B |
|
click to enlarge
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Title
|
Crystal Structure of human peroxisomal acetyl-CoA acyl transferase 1 (ACAA1) |
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Classification
|
TRANSFERASE |
|
Compound
|
3-ketoacyl-CoA thiolase, peroxisomal |
|
Source
|
null (THIK_HUMAN) |
|
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Sequence
|
B: |
TENLYFQSMAPQASAADVVVVHGRRTAICRAGRGGFKDTT
PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIM
ARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNG
SYDIGMACGVESMSLAPGNITSRLMEKEKARDCLIPMGIT
SENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIV
PVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAF
KKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVL
RSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEI
NEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGA
RQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN
|
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Description
|
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Functional site
|
|
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1)
|
chain |
B |
| residue |
125 |
| type |
ACT_SITE |
| sequence |
S
|
| description |
Acyl-thioester intermediate => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
380 |
| type |
ACT_SITE |
| sequence |
L
|
| description |
Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10020
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
B |
| residue |
411 |
| type |
ACT_SITE |
| sequence |
G
|
| description |
Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10020
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
B |
| residue |
61 |
| type |
MOD_RES |
| sequence |
P
|
| description |
Phosphothreonine => ECO:0007744|PubMed:19690332
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
B |
| residue |
62 |
| type |
MOD_RES |
| sequence |
D
|
| description |
Phosphothreonine => ECO:0007744|PubMed:19690332
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|