|
|
eF-site ID
|
2ifg-E |
|
PDB Code
|
2ifg |
|
Chain
|
E |
|
click to enlarge
|
|
|
Title
|
Structure of the extracellular segment of human TRKA in complex with nerve growth factor |
|
Classification
|
TRANSFERASE |
|
Compound
|
High affinity nerve growth factor receptor |
|
Source
|
(NGF_HUMAN) |
|
|
Sequence
|
E: |
SSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGE
VNINNSVFKQYFFETKCRDGCRGIDSKHWNSYCTTTHTFV
KALTMDGKQAAWRFIRIDTACVCVLSRK
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
E |
| residue |
52 |
| type |
BINDING |
| sequence |
Y
|
| description |
in other chain => ECO:0000250|UniProtKB:P01139
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
E |
| residue |
88 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000250|UniProtKB:P01139
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
E |
| residue |
67-80 |
| type |
prosite |
| sequence |
GCRGIDSKHWNSYC
|
| description |
NGF_1 Nerve growth factor family signature. GCRGIDskhWnSyC
|
| source |
prosite : PS00248
|
|
|
|