|
|
eF-site ID
|
2iff-Y |
|
PDB Code
|
2iff |
|
Chain
|
Y |
|
click to enlarge
|
|
|
Title
|
STRUCTURE OF AN ANTIBODY-LYSOZYME COMPLEX: EFFECT OF A CONSERVATIVE MUTATION |
|
Classification
|
IMMUNOGLOBULIN/HYDROLASE(O-GLYCOSYL) |
|
Compound
|
IGG1 HYHEL-5 FAB (LIGHT CHAIN) |
|
Source
|
null (2IFF) |
|
|
Sequence
|
Y: |
KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNT
QATNRNTDGSTDYGILQINSRWWCNDGKTPGSRNLCNIPC
SALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDV
QAWIRGCRL
|
|
|
Description
|
(1) |
IGG1 FAB FRAGMENT (HYHEL-5) COMPLEXED WITH LYSOZYME MUTANT WITH ARG 68 REPLACED BY LYS (R68K)
|
|
Functional site
|
|
|
1)
|
chain |
Y |
| residue |
76-94 |
| type |
prosite |
| sequence |
CNIPCSALLSSDITASVNC
|
| description |
GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC
|
| source |
prosite : PS00128
|
|
|
2)
|
chain |
Y |
| residue |
35 |
| type |
catalytic |
| sequence |
E
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
3)
|
chain |
Y |
| residue |
46 |
| type |
catalytic |
| sequence |
N
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
4)
|
chain |
Y |
| residue |
48 |
| type |
catalytic |
| sequence |
D
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
Y |
| residue |
50 |
| type |
catalytic |
| sequence |
S
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
6)
|
chain |
Y |
| residue |
52 |
| type |
catalytic |
| sequence |
D
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
7)
|
chain |
Y |
| residue |
59 |
| type |
catalytic |
| sequence |
N
|
| description |
203
|
| source |
MCSA : MCSA1
|
|
|
8)
|
chain |
Y |
| residue |
35 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
Y |
| residue |
52 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
Y |
| residue |
101 |
| type |
BINDING |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|