eF-site ID 2ibi-A PDB Code 2ibi Chain A click to enlarge Title Covalent Ubiquitin-USP2 Complex Classification HYDROLASE Compound Ubiquitin carboxyl-terminal hydrolase 2 Source Homo sapiens (Human) (UBIQ_HUMAN) Sequence A:  AQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMR DLHHGSNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQ IQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKN PENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSL TCTDCGYCSTVFDPFWDLSLPIAKRGPEVTLMDCMRLFTK EDVLDGDAAPTCCRCRGRKRCIKKFSIQRFPKILVLHLKR FSESRIRTSKLTTFVNFPLRDLDLREFASENTHAVYNLYA VSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQ VRTSDAYLLFYELAS Description Functional site 1) chain A residue 425 type sequence C description BINDING SITE FOR RESIDUE ZN A 1 source : AC1 2) chain A residue 428 type sequence C description BINDING SITE FOR RESIDUE ZN A 1 source : AC1 3) chain A residue 476 type sequence C description BINDING SITE FOR RESIDUE ZN A 1 source : AC1 4) chain A residue 479 type sequence C description BINDING SITE FOR RESIDUE ZN A 1 source : AC1 5) chain A residue 274 type sequence N description BINDING SITE FOR RESIDUE NEH B 76 source : AC2 6) chain A residue 276 type sequence C description BINDING SITE FOR RESIDUE NEH B 76 source : AC2 7) chain A residue 355 type sequence Q description BINDING SITE FOR RESIDUE NEH B 76 source : AC2 8) chain A residue 556 type sequence G description BINDING SITE FOR RESIDUE NEH B 76 source : AC2 9) chain A residue 557 type sequence H description BINDING SITE FOR RESIDUE NEH B 76 source : AC2 10) chain A residue 268-283 type prosite sequence GLRNLGNTCFMNSILQ description USP_1 Ubiquitin specific protease (USP) domain signature 1. GLrnlGNtCFMNSiLQ source prosite : PS00972 11) chain A residue 541-558 type prosite sequence YNLYAVSNHSGTTMGGHY description USP_2 Ubiquitin specific protease (USP) domain signature 2. YnLyAVsnHsGttmg..GHY source prosite : PS00973 12) chain A residue 429 type MOD_RES sequence G description Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291 source Swiss-Prot : SWS_FT_FI3 13) chain A residue 477 type MOD_RES sequence C description Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291 source Swiss-Prot : SWS_FT_FI3 14) chain A residue 480 type MOD_RES sequence R description Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291 source Swiss-Prot : SWS_FT_FI3

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