eF-site ID 2i28_2-A
PDB Code 2i28
Model 2
Chain A

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Title Solution Structure of alpha-Conotoxin BuIA
Classification TOXIN
Compound Alpha-conotoxin BuIA
Source Conus bullatus (Bubble cone) (CXA1_CONBU)
Sequence A:  GCCSTPPCAVLYCX
Description


Functional site

1) chain A
residue 8
type
sequence C
description BINDING SITE FOR RESIDUE NH2 A 14
source : AC1

2) chain A
residue 12
type
sequence Y
description BINDING SITE FOR RESIDUE NH2 A 14
source : AC1

3) chain A
residue 13
type
sequence C
description BINDING SITE FOR RESIDUE NH2 A 14
source : AC1

4) chain A
residue 13
type MOD_RES
sequence C
description Cysteine amide => ECO:0000305|PubMed:15520009, ECO:0000305|PubMed:16964981, ECO:0000305|PubMed:16979596, ECO:0000305|PubMed:17445276, ECO:0000305|PubMed:20739611
source Swiss-Prot : SWS_FT_FI2

5) chain A
residue 2-13
type prosite
sequence CCSTPPCAVLYC
description ALPHA_CONOTOXIN Alpha-conotoxin family signature. CCStPPCAv...LYC
source prosite : PS60014

6) chain A
residue 6
type SITE
sequence P
description Critical residue for distinguishing between alpha-6-beta-2/CHRNA6-CHRNB2 and alpha-6-beta-4/CHRNA6-CHRNB4 nAChR subunits => ECO:0000269|PubMed:20739611
source Swiss-Prot : SWS_FT_FI1


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