|
|
eF-site ID
|
2i1y-B |
|
PDB Code
|
2i1y |
|
Chain
|
B |
|
click to enlarge
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Title
|
Crystal structure of the phosphatase domain of human PTP IA-2 |
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Classification
|
HYDROLASE |
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Compound
|
Receptor-type tyrosine-protein phosphatase |
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Source
|
(PTPRN_HUMAN) |
|
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Sequence
|
B: |
MDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQAEPNTC
ATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYIN
ASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVI
VMLTPLVEDGVKQCDRYWPDEGASLYHVYEVNLVSEHIWC
EDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRP
LLDFRRKVNKCYRGRSCPIIVHCSDGAGRTGTYILIDMVL
NRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAV
AEEVNAILKA
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
926 |
| type |
|
| sequence |
L
|
| description |
BINDING SITE FOR RESIDUE GOL B 3287
|
| source |
: AC2
|
|
|
2)
|
chain |
B |
| residue |
929 |
| type |
|
| sequence |
M
|
| description |
BINDING SITE FOR RESIDUE GOL B 3287
|
| source |
: AC2
|
|
|
3)
|
chain |
B |
| residue |
970 |
| type |
|
| sequence |
V
|
| description |
BINDING SITE FOR RESIDUE GOL B 3287
|
| source |
: AC2
|
|
|
4)
|
chain |
B |
| residue |
973 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR RESIDUE GOL B 3287
|
| source |
: AC2
|
|
|
5)
|
chain |
B |
| residue |
754 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:16622421
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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