|
|
eF-site ID
|
2hty-E |
|
PDB Code
|
2hty |
|
Chain
|
E |
|
click to enlarge
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Title
|
N1 neuraminidase |
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Classification
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HYDROLASE |
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Compound
|
Neuraminidase |
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Source
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ORGANISM_SCIENTIFIC: Influenza A virus; |
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Sequence
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E: |
VKLAGNSSLCPINGWAVYSKDNSIRIGSKGDVFVIREPFI
SCSHLECRTFFLTQGALLNDKHSNGTVKDRSPHRTLMSCP
VGEAPSPYNSRFESVAWSASACHDGTSWLTIGISGPDNGA
VAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVM
TDGPSNGQASYKIFKMEKGKVVKSVELDAPNYHYEECSCY
PNAGEITCVCRDNWHGSNRPWVSFNQNLEYQIGYICSGVF
GDNPRPNDGTGSCGPVSSNGAYGVKGFSFKYGNGVWIGRT
KSTNSRSGFEMIWDPNGWTETDSSFSVKQDIVAITDWSGY
SGSFVQHPELTGLDCIRPCFWVELIRGRPKESTIWTSGSS
ISFCGVNSDTVGWSWPDGAELPFTI
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Description
|
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Functional site
|
|
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1)
|
chain |
E |
| residue |
151 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04071
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
E |
| residue |
406 |
| type |
ACT_SITE |
| sequence |
Y
|
| description |
Nucleophile => ECO:0000255|HAMAP-Rule:MF_04071
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
E |
| residue |
118 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04071
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
E |
| residue |
152 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04071
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
E |
| residue |
276 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04071
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
E |
| residue |
292 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04071
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
7)
|
chain |
E |
| residue |
371 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04071
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
8)
|
chain |
E |
| residue |
293 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:16915235, ECO:0000269|PubMed:18480754, ECO:0007744|PDB:2HTY, ECO:0007744|PDB:3CKZ, ECO:0007744|PDB:3CL0
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
9)
|
chain |
E |
| residue |
297 |
| type |
BINDING |
| sequence |
G
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:16915235, ECO:0000269|PubMed:18480754, ECO:0007744|PDB:2HTY, ECO:0007744|PDB:3CKZ, ECO:0007744|PDB:3CL0
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
10)
|
chain |
E |
| residue |
324 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:16915235, ECO:0000269|PubMed:18480754, ECO:0007744|PDB:2HTY, ECO:0007744|PDB:3CKZ, ECO:0007744|PDB:3CL0
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
11)
|
chain |
E |
| residue |
345 |
| type |
BINDING |
| sequence |
G
|
| description |
BINDING => ECO:0000269|PubMed:16915235, ECO:0000269|PubMed:18480754, ECO:0007744|PDB:2HTY, ECO:0007744|PDB:3CKZ, ECO:0007744|PDB:3CL0
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
12)
|
chain |
E |
| residue |
347 |
| type |
BINDING |
| sequence |
Y
|
| description |
BINDING => ECO:0000269|PubMed:16915235, ECO:0000269|PubMed:18480754, ECO:0007744|PDB:2HTY, ECO:0007744|PDB:3CKZ
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
|