eF-site ID 2hqu-C PDB Code 2hqu Chain C click to enlarge Title Human dUTPase in complex with alpha,beta-iminodUTP and magnesium ion Classification HYDROLASE Compound Deoxyuridine 5'-triphosphate nucleotidohydrolase Source Homo sapiens (Human) (DUT_HUMAN) Sequence C:  MQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEK AVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDE DYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIE EVQF Description Functional site 1) chain C residue 95 type sequence D description BINDING SITE FOR RESIDUE MG A 998 source : AC4 2) chain C residue 72 type sequence I description BINDING SITE FOR RESIDUE CL C 999 source : AC5 3) chain C residue 74 type sequence L description BINDING SITE FOR RESIDUE CL C 999 source : AC5 4) chain C residue 102 type sequence D description BINDING SITE FOR RESIDUE CL C 999 source : AC5 5) chain C residue 103 type sequence E description BINDING SITE FOR RESIDUE CL C 999 source : AC5 6) chain C residue 105 type sequence Y description BINDING SITE FOR RESIDUE CL C 999 source : AC5 7) chain C residue 106 type sequence R description BINDING SITE FOR RESIDUE CL C 999 source : AC5 8) chain C residue 158 type sequence F description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 9) chain C residue 85 type sequence R description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 10) chain C residue 86 type sequence S description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 11) chain C residue 87 type sequence G description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 12) chain C residue 131 type sequence Q description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 13) chain C residue 98 type sequence A description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 14) chain C residue 99 type sequence G description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 15) chain C residue 100 type sequence V description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 16) chain C residue 101 type sequence I description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 17) chain C residue 102 type sequence D description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 18) chain C residue 105 type sequence Y description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 19) chain C residue 110 type sequence G description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 20) chain C residue 80 type BINDING sequence G description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI1 21) chain C residue 94 type BINDING sequence I description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3ARA, ECO:0007744|PDB:3ARN, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI2 22) chain C residue 105 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3ARA, ECO:0007744|PDB:3ARN, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI2

Display surface Download Links