eF-site ID 2hqu-B PDB Code 2hqu Chain B click to enlarge Title Human dUTPase in complex with alpha,beta-iminodUTP and magnesium ion Classification HYDROLASE Compound Deoxyuridine 5'-triphosphate nucleotidohydrolase Source null (DUT_HUMAN) Sequence B:  MQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEK AVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDE DYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIE EVQALDDTERGSGGFGSTGKN Description Functional site 1) chain B residue 98 type sequence A description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 2) chain B residue 99 type sequence G description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 3) chain B residue 100 type sequence V description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 4) chain B residue 101 type sequence I description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 5) chain B residue 102 type sequence D description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 6) chain B residue 105 type sequence Y description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 7) chain B residue 110 type sequence G description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 8) chain B residue 153 type sequence R description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 9) chain B residue 157 type sequence G description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 10) chain B residue 158 type sequence F description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 11) chain B residue 159 type sequence G description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 12) chain B residue 160 type sequence S description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 13) chain B residue 161 type sequence T description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 14) chain B residue 85 type sequence R description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 15) chain B residue 86 type sequence S description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 16) chain B residue 87 type sequence G description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 17) chain B residue 131 type sequence Q description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 18) chain B residue 85 type BINDING sequence R description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI1 19) chain B residue 153 type BINDING sequence R description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI1 20) chain B residue 158 type BINDING sequence F description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI1 21) chain B residue 99 type BINDING sequence G description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3ARA, ECO:0007744|PDB:3ARN, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI2 22) chain B residue 110 type BINDING sequence G description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3ARA, ECO:0007744|PDB:3ARN, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI2

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