eF-site ID 2hqu-A PDB Code 2hqu Chain A click to enlarge Title Human dUTPase in complex with alpha,beta-iminodUTP and magnesium ion Classification HYDROLASE Compound Deoxyuridine 5'-triphosphate nucleotidohydrolase Source Homo sapiens (Human) (DUT_HUMAN) Sequence A:  MQLRFARLSEHATAPTRRAAGYDLYSAYDYTIPPMEKAVV KTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYR GNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQ ALDDTERGSGGFGSTGKN Description Functional site 1) chain A residue 95 type sequence D description BINDING SITE FOR RESIDUE MG A 998 source : AC4 2) chain A residue 85 type sequence R description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 3) chain A residue 86 type sequence S description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 4) chain A residue 87 type sequence G description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 5) chain A residue 131 type sequence Q description BINDING SITE FOR RESIDUE DUP A 777 source : AC6 6) chain A residue 98 type sequence A description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 7) chain A residue 99 type sequence G description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 8) chain A residue 100 type sequence V description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 9) chain A residue 101 type sequence I description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 10) chain A residue 102 type sequence D description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 11) chain A residue 105 type sequence Y description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 12) chain A residue 110 type sequence G description BINDING SITE FOR RESIDUE DUP B 777 source : AC7 13) chain A residue 153 type sequence R description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 14) chain A residue 157 type sequence G description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 15) chain A residue 158 type sequence F description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 16) chain A residue 159 type sequence G description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 17) chain A residue 160 type sequence S description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 18) chain A residue 161 type sequence T description BINDING SITE FOR RESIDUE DUP C 777 source : AC8 19) chain A residue 85 type BINDING sequence R description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI1 20) chain A residue 153 type BINDING sequence R description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI1 21) chain A residue 158 type BINDING sequence F description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI1 22) chain A residue 99 type BINDING sequence G description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3ARA, ECO:0007744|PDB:3ARN, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI2 23) chain A residue 110 type BINDING sequence G description BINDING => ECO:0000269|PubMed:8805593, ECO:0000305|PubMed:17880943, ECO:0007744|PDB:1Q5H, ECO:0007744|PDB:2HQU, ECO:0007744|PDB:3ARA, ECO:0007744|PDB:3ARN, ECO:0007744|PDB:3EHW source Swiss-Prot : SWS_FT_FI2

Display surface Download Links