eF-site ID 2hp4-A PDB Code 2hp4 Chain A click to enlarge Title Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor Classification IMMUNE SYSTEM Compound T-cell surface glycoprotein CD8 alpha chain Source Homo sapiens (Human) (CD8A_HUMAN) Sequence A:  SQFRVSPLDRTWNLGETVELKCQVLLSNPTSGASWLFQPR GAAASPTFLLYLNQNKPKAAEGLDTQRFSGKRLGDTFVLT LSDFRRENEGYYFCSALSNSIMYFSHFVPVFLPA Description Functional site 1) chain A residue 4 type sequence R description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 2) chain A residue 7 type sequence P description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 3) chain A residue 10 type sequence R description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 4) chain A residue 21 type sequence K description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 5) chain A residue 53 type sequence N description BINDING SITE FOR RESIDUE SO4 A 304 source : AC4 6) chain A residue 54 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 304 source : AC4 7) chain A residue 55 type sequence N description BINDING SITE FOR RESIDUE SO4 A 304 source : AC4 8) chain A residue 23 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 305 source : AC5 9) chain A residue 74 type sequence G description BINDING SITE FOR RESIDUE SO4 A 305 source : AC5 10) chain A residue 75 type sequence D description BINDING SITE FOR RESIDUE SO4 A 305 source : AC5 11) chain A residue 76 type sequence T description BINDING SITE FOR RESIDUE SO4 A 305 source : AC5 12) chain A residue 1 type sequence S description BINDING SITE FOR RESIDUE GOL A 401 source : AC6 13) chain A residue 106 type sequence H description BINDING SITE FOR RESIDUE GOL A 401 source : AC6 14) chain A residue 37 type sequence F description BINDING SITE FOR RESIDUE GOL A 403 source : AC8 15) chain A residue 47 type sequence T description BINDING SITE FOR RESIDUE GOL A 403 source : AC8 16) chain A residue 49 type sequence L description BINDING SITE FOR RESIDUE GOL A 403 source : AC8 17) chain A residue 68 type sequence F description BINDING SITE FOR RESIDUE GOL A 403 source : AC8 18) chain A residue 88 type sequence N description BINDING SITE FOR RESIDUE GOL A 403 source : AC8 19) chain A residue 92 type sequence Y description BINDING SITE FOR RESIDUE GOL A 403 source : AC8

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