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eF-site ID
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2hle-AB |
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PDB Code
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2hle |
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Chain
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A, B |
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click to enlarge
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Title
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Structural and biophysical characterization of the EPHB4-EPHRINB2 protein protein interaction and receptor specificity. |
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Classification
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TRANSFERASE/TRANSFERASE RECEPTOR |
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Compound
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Ephrin type-B receptor 4 |
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Source
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Homo sapiens (Human) (EFNB2_HUMAN) |
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Sequence
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A: |
AGHHHHHHEETLLNTKLETADLKWVTFPQVDGQWEELSGL
DEEQHSVRTYEVCDVQRAPGQAHWLRTGWVPRRGAVHVYA
TLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTP
AWMENPYIKVDTVAAEHLTRKRPGAEATGKVNVKTLRLGP
LSKAGFYLAFQDQGACMALLSLHLFYKK
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| B: |
IVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDIICPKVDS
KTVQYEYYKVYMVDKDQADRCTIKPLLNCARPDQDVKFTI
KFQEFSPNLWGLEFQKNKDYYIISTSNGSLEGLDNQEGGV
CQTRAMKILMKVG
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Description
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Functional site
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1)
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chain |
B |
| residue |
39 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000255, ECO:0000269|PubMed:18488039, ECO:0000269|PubMed:19836338
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
B |
| residue |
142 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
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3)
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chain |
B |
| residue |
112-139 |
| type |
prosite |
| sequence |
KFTIKFQEFSPNLWGLEFQKNKDYYIIS
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| description |
EPHRIN_RBD_1 Ephrin receptor-binding (ephrin RBD) domain signature. KFTiKFQeFSPnlwGlEFqknkdYYiiS
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| source |
prosite : PS01299
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