eF-site ID 2hhl-A
PDB Code 2hhl
Chain A

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Title Crystal structure of the human small CTD phosphatase 3 isoform 1
Classification HYDROLASE
Compound CTD small phosphatase-like protein
Source (CTDSL_HUMAN)
Sequence A:  QVIPIPSPPAKYLLPEVTVLDYGKKCVVIDLDETLVHSSF
KPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLF
ECVLFTASLAKYADPVADLLDRWGVFRARLFRESCVFHRG
NYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQSWF
DDMTDTELLDLIPFFEGLSR
Description


Functional site

1) chain A
residue 26
type
sequence Y
description BINDING SITE FOR RESIDUE KEG A 902
source : AC1

2) chain A
residue 27
type
sequence G
description BINDING SITE FOR RESIDUE KEG A 902
source : AC1

3) chain A
residue 28
type
sequence K
description BINDING SITE FOR RESIDUE KEG A 902
source : AC1

4) chain A
residue 41
type
sequence H
description BINDING SITE FOR RESIDUE KEG A 902
source : AC1

5) chain A
residue 43
type
sequence S
description BINDING SITE FOR RESIDUE KEG A 902
source : AC1

6) chain A
residue 44
type
sequence F
description BINDING SITE FOR RESIDUE KEG A 902
source : AC1

7) chain A
residue 45
type
sequence K
description BINDING SITE FOR RESIDUE KEG A 902
source : AC1

8) chain A
residue 55
type
sequence P
description BINDING SITE FOR RESIDUE KEG C 900
source : AC2

9) chain A
residue 62
type
sequence I
description BINDING SITE FOR RESIDUE KEG C 900
source : AC2

10) chain A
residue 64
type
sequence Q
description BINDING SITE FOR RESIDUE KEG C 900
source : AC2

11) chain A
residue 34
type ACT_SITE
sequence D
description 4-aspartylphosphate intermediate => ECO:0000250
source Swiss-Prot : SWS_FT_FI1

12) chain A
residue 36
type ACT_SITE
sequence D
description Proton donor => ECO:0000250
source Swiss-Prot : SWS_FT_FI2

13) chain A
residue 34
type BINDING
sequence D
description BINDING => ECO:0000250
source Swiss-Prot : SWS_FT_FI3

14) chain A
residue 36
type BINDING
sequence D
description BINDING => ECO:0000250
source Swiss-Prot : SWS_FT_FI3

15) chain A
residue 145
type BINDING
sequence N
description BINDING => ECO:0000250
source Swiss-Prot : SWS_FT_FI3

16) chain A
residue 90
type SITE
sequence T
description Transition state stabilizer => ECO:0000250
source Swiss-Prot : SWS_FT_FI4

17) chain A
residue 128
type SITE
sequence K
description Transition state stabilizer => ECO:0000250
source Swiss-Prot : SWS_FT_FI4


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