eF-site ID 2hhd-C PDB Code 2hhd Chain C click to enlarge Title OXYGEN AFFINITY MODULATION BY THE N-TERMINI OF THE BETA-CHAINS IN HUMAN AND BOVINE HEMOGLOBIN Classification OXYGEN TRANSPORT Compound HEMOGLOBIN (DEOXY) (ALPHA CHAIN) Source Homo sapiens (Human) (HBB_HUMAN) Sequence C:  VLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTK TYFPHFDLSHGSAQVKGHGKKVADALTNAVAHVDDMPNAL SALSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPA VHASLDKFLASVSTVLTSKYR Description Functional site 1) chain C residue 42 type sequence Y description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 2) chain C residue 43 type sequence F description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 3) chain C residue 45 type sequence H description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 4) chain C residue 46 type sequence F description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 5) chain C residue 58 type sequence H description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 6) chain C residue 61 type sequence K description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 7) chain C residue 83 type sequence L description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 8) chain C residue 86 type sequence L description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 9) chain C residue 87 type sequence H description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 10) chain C residue 91 type sequence L description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 11) chain C residue 93 type sequence V description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 12) chain C residue 97 type sequence N description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 13) chain C residue 98 type sequence F description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 14) chain C residue 136 type sequence L description BINDING SITE FOR RESIDUE HEM C 142 source : AC5 15) chain C residue 9 type MOD_RES sequence N description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 16) chain C residue 14 type MOD_RES sequence W description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 17) chain C residue 25 type MOD_RES sequence G description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 18) chain C residue 30 type MOD_RES sequence E description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 19) chain C residue 46 type MOD_RES sequence F description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 20) chain C residue 48 type MOD_RES sequence L description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 21) chain C residue 53 type MOD_RES sequence A description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 22) chain C residue 56 type MOD_RES sequence K description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 23) chain C residue 60 type MOD_RES sequence K description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 24) chain C residue 92 type MOD_RES sequence R description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 25) chain C residue 107 type MOD_RES sequence V description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 26) chain C residue 109 type MOD_RES sequence L description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 27) chain C residue 122 type MOD_RES sequence H description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 28) chain C residue 134 type MOD_RES sequence T description S-nitrosocysteine => ECO:0000269|PubMed:8637569, ECO:0000269|PubMed:9843411 source Swiss-Prot : SWS_FT_FI10 29) chain C residue 100 type MOD_RES sequence L description N6-acetyllysine; alternate => ECO:0000269|PubMed:4531009 source Swiss-Prot : SWS_FT_FI11 30) chain C residue 12 type MOD_RES sequence A description N6-acetyllysine; alternate => ECO:0000269|PubMed:4531009 source Swiss-Prot : SWS_FT_FI11 31) chain C residue 57 type MOD_RES sequence G description N6-acetyllysine; alternate => ECO:0000269|PubMed:4531009 source Swiss-Prot : SWS_FT_FI11 32) chain C residue 61 type MOD_RES sequence K description N6-acetyllysine; alternate => ECO:0000269|PubMed:4531009 source Swiss-Prot : SWS_FT_FI11 33) chain C residue 91 type MOD_RES sequence L description N6-acetyllysine; alternate => ECO:0000269|PubMed:4531009 source Swiss-Prot : SWS_FT_FI11 34) chain C residue 4 type BINDING sequence P description proximal binding residue source Swiss-Prot : SWS_FT_FI3 35) chain C residue 36 type BINDING sequence F description proximal binding residue source Swiss-Prot : SWS_FT_FI3 36) chain C residue 50 type BINDING sequence H description proximal binding residue source Swiss-Prot : SWS_FT_FI3 37) chain C residue 132 type MOD_RES sequence V description Phosphothreonine => ECO:0007744|PubMed:24275569 source Swiss-Prot : SWS_FT_FI8 38) chain C residue 139 type MOD_RES sequence K description Phosphothreonine => ECO:0007744|PubMed:24275569 source Swiss-Prot : SWS_FT_FI8 39) chain C residue 135 type MOD_RES sequence V description N6-acetyllysine => ECO:0000269|PubMed:4531009 source Swiss-Prot : SWS_FT_FI9 40) chain C residue 138 type MOD_RES sequence S description N6-acetyllysine => ECO:0000269|PubMed:4531009 source Swiss-Prot : SWS_FT_FI9 41) chain C residue 8 type CARBOHYD sequence T description N-linked (Glc) (glycation) valine; in Hb A1c => ECO:0000269|PubMed:635569 source Swiss-Prot : SWS_FT_FI12 42) chain C residue 17 type CARBOHYD sequence V description N-linked (Glc) (glycation) valine; in Hb A1c => ECO:0000269|PubMed:635569 source Swiss-Prot : SWS_FT_FI12 43) chain C residue 41 type CARBOHYD sequence T description N-linked (Glc) (glycation) valine; in Hb A1c => ECO:0000269|PubMed:635569 source Swiss-Prot : SWS_FT_FI12

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