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eF-site ID
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2hdx-ABCDEFGHIJKL |
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PDB Code
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2hdx |
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Chain
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A, B, C, D, E, F, G, H, I, J, K, L |
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click to enlarge
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Title
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Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide |
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Classification
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SIGNALING PROTEIN |
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Compound
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SH2-B PH domain containing signaling mediator 1 gamma isoform |
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Source
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(Q7TQD0_MOUSE) |
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Sequence
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A: |
QPLSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSET
RRGECVLTFNFQGKAKHLRLSLNAAGQCRVQHLHFQSIFD
MLEHFRVHPIPLESGGSSDVVLVSYVPS
|
| B: |
QPLSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSET
RRGECVLTFNFQGKAKHLRLSLNAAGQCRVQHLHFQSIFD
MLEHFRVHPIPLESSDVVLVSYVPS
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| C: |
QPLSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSET
RRGECVLTFNFQGKAKHLRLSLNAAGQCRVQHLHFQSIFD
MLEHFRVHPIPLESGGSSDVVLVSYVPS
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| D: |
QPLSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSET
RRGECVLTFNFQGKAKHLRLSLNAAGQCRVQHLHFQSIFD
MLEHFRVHPIPLESSDVVLVSYVPS
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| E: |
QPLSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSET
RRGECVLTFNFQGKAKHLRLSLNAAGQCRVQHLHFQSIFD
MLEHFRVHPIPLESGGSSDVVLVSYVPS
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| F: |
QPLSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSET
RRGECVLTFNFQGKAKHLRLSLNAAGQCRVQHLHFQSIFD
MLEHFRVHPIPLESDVVLVSYVPS
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| G: |
TPDXELLTE
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| H: |
DXELLTE
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| I: |
DXELLTE
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| J: |
DXELLTE
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| K: |
DXELLTE
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| L: |
TPDXELLTE
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Description
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Functional site
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|
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1)
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chain |
G |
| residue |
813 |
| type |
MOD_RES |
| sequence |
X
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| description |
Phosphotyrosine => ECO:0000269|PubMed:16824542, ECO:0000269|PubMed:17565041
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
H |
| residue |
813 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine => ECO:0000269|PubMed:16824542, ECO:0000269|PubMed:17565041
|
| source |
Swiss-Prot : SWS_FT_FI1
|
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3)
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chain |
I |
| residue |
813 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine => ECO:0000269|PubMed:16824542, ECO:0000269|PubMed:17565041
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| source |
Swiss-Prot : SWS_FT_FI1
|
|
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4)
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chain |
J |
| residue |
813 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine => ECO:0000269|PubMed:16824542, ECO:0000269|PubMed:17565041
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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5)
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chain |
K |
| residue |
813 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine => ECO:0000269|PubMed:16824542, ECO:0000269|PubMed:17565041
|
| source |
Swiss-Prot : SWS_FT_FI1
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6)
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chain |
L |
| residue |
813 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine => ECO:0000269|PubMed:16824542, ECO:0000269|PubMed:17565041
|
| source |
Swiss-Prot : SWS_FT_FI1
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